CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Farmácia e Bioquímica from Universidade Estadual Paulista Júlio de Mesquita Filho (1998), master's at General Biology from Universidade Estadual Paulista Júlio de Mesquita Filho (2001) and ph.d. at Fisiologia Humana from Universidade de São Paulo (2007). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: eIF5A. (Source: Lattes Curriculum)
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In the mid-19th century, a European expedition in the "Brazilian province of Matto Grosso" discovered for the first time the aquatic plant Wolffia brasiliensis, which is considered the smallest angiosperm with fronds in the plant kingdom, measuring around 1 mm. W. brasiliensis can be found floating in lakes and rivers and plays an important role in aquatic ecosystems, providing shelter an…
The amino acid hypusine was first identified in 1971 from bovine brain extract. Later, this amino acid was found in liver, kidney, muscle and blood of other mammals. In addition, hypusine is a substrate to synthesise the ±-(³-aminobutyryl)-hypusine (GABA-hypusine) dipeptide. The GABA is the most representative inhibitory neurotransmitter of the central nervous system. It is noted that the…
The eukaryotic translation initiation factor 5A (eIF5A) protein is highly conserved, been produced by archaea and eukaryotes. This factor possesses a particular amino acid residue named hypusine that is not found in others proteins. The hypusine is essential for its activity and is formed by a post translational modification, using spermidine as substrate, called hypusination. The eIF5A p…
(Only some records are available in English at this moment)
The use of macrophyte type aquatic plants for phytoremediation of environmental contaminants represents a platform with great potential for removal of eutrophic compounds, nitrogen (N) and phosphorus (P), as well as other pollutants. In this context, phytoremediation can efficiently reduce environmental contaminants, and the aquatic plant behaves as a photosynthetic pump capable of adsorb…
Some aquatic plant species of the macrophyte type can be used in bioremediation platforms, acting in the purification of water contaminated by different chemical agents. In addition, members of the Lemnoideae subfamily have been used as a food source in some Asian countries, with emphasis on the interest in the content of their proteins of high nutritional value. The production of Lemnoid…
The Leukocyte Secretory Protease Inhibitor (SLPI) is a non-glycosylated cationic protein with action against serine protease, serving to control the excessive release of secreted proteases such as trypsin, chymotrypsin, elastase and cathepsin G from mammal. In addition to its antiprotease activity, SLPI has been shown to express antibacterial, antiviral, antifungal and anti-inflammatory p…
The amino acid hypusine was first described in 1971, from bovine brain. Later, the hypusine was found in other mammalian tissues, like liver, kidney, muscle, and blood. In addition to being found in its free form, the hypusine is an amino acid residue present in eukaryotic translation initiation factor 5A (eIF5A). The eIF5A is the unique protein described that contains hypusine, produced …
(Only some records are available in English at this moment)
Algae are a promising platform for producing a broad range of bio-products including recombinant proteins for animal feed supplements or pharmaceutical applications. Scalable and low-cost production platforms are of growing importance for the development of affordable recombinant proteins, especially proteins that require large dosing regimens and/or have large patient populations. Curren…
The eukaryotic translation initiation factor 5A (eIF5A) is highly conserved in archaea and eukaryotes, and is the only protein containing the amino acid residue hypusine, which is required for its activity. eIF5A has been involved in different points of the gene expression control, such as transcription, nuclear pore transport, nonsense-mediated decay (NMD), and translation. In addition, …
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 12 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 20 / 16 | All research grants and scholarships |
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