CV Lattes
ORCID
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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Odontologia from Universidade de São Paulo (1997), master's at Pathological Anatomy and Clinical Pathology from Universidade de São Paulo (2001) and doctorate at Pathological Anatomy and Clinical Pathology from Universidade de São Paulo (2003). Has experience in Immunology, acting on the following subjects: células endoteliais, ischemia/reperfusão intestinal, inflamação pulmonar, biomateriais and integrinas. (Source: Lattes Curriculum)
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Organ transplantation is a treatment option for patients in advanced stages of the disease, however the reduced number of available organs is an obstacle to its effectiveness. Current data show that there is a great difference between the number of patients who need an organ for transplantation and the number of possible donors. In Brazil, in 2021, the number of potential donors was 5,846…
Surgical procedures involving aortic obstruction may present complications, such as ischemia and reperfusion injury. This clinical condition consists of the occlusion of the blood flow and its subsequent return to the tissue, resulting in hemodynamic changes, activation of the immune system and, in extreme cases, severe tissue lesions. Some inflammatory responses are so exacerbated that, …
Organ transplantation from brain dead individuals is the possible treatment for many patients in endstage of disease. The lung is one of the most affected organs by the brain death, which is associated to hemodynamic instability and inflammatory and immunological alterations, affecting the organs quality for transplantation. Studies highlight the worse outcome of lung transplant with fema…
The organ transplantation has evolved as the treatment of choice for many patients with end-stage disease. However, clinical studies show differences in the prognosis of short and long-term transplants due to donor gender. Clinical and experimental evidence also highlight the impact of brain death on the viability of the organ to be transplanted and show the importance of the donor state …
Organ transplantation is a treatment option for patients in advanced stages of the disease, however the reduced number of available organs is an obstacle. The high demand of patients on the waiting list for organs means that criteria for the use of marginal donors are becoming more flexible and among these donors, with the aging of the population, there is the inclusion of older donors. B…
Organ transplantation from Brain Dead (BD) individuals is the possible treatment for many patients in endstage of disease. Several studies highlight the impact of brain death on organ viability. BD leads to a systemic inflammatory process associated with hormonal, metabolic and hemodynamic changes. The lung is one of the organs most affected by brain death. Previous studies of pulmonary i…
Organ transplantation from Brain Dead (BD) individuals is the possible treatment for many pulmonary advanced diseases and could improve the life quality and extend survival. Clinical and experimental studies evidenced the BD impact on transplanted organ viability. Also the lung is one the most affected organs by BD, which is associated with hemodynamic instability and inflammatory and imm…
The organ transplantation is the treatment of choice for many patients with end-stage disease, where brain death (BD) patients are the main source of transplantation. Clinical and experimental evidence highlight the impact of BD on organ viability to transplant. BD triggers immune system activation, with expression of endothelial adhesion molecules, release of cytokines, chemokines and wi…
(Only some records are available in English at this moment)
Organ transplantation is the possible treatment for many patients in endstage of disease, and the majority of organs are obtained from brain dead patients. Brain death (BD) leads to a systemic inflammatory process associated with hormonal, metabolic and hemodynamic changes and the lung is one of the organs most affected. Previous studies of pulmonary inflammation caused by BD, showed a mo…
Lung transplant, which often comes from brain dead (BD) donors, is the treatment of choice for severe lung disease. However the low numbers of viable lungs for transplantation impacts on the patient treatment capacity. Clinical and experimental studies highlight the impact of BD on lung viability for transplant, starting with the hemodynamic instability and inflammatory and immunological …
| 1 / 1 | Ongoing grants |
| 3 / 3 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 6 / 5 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 13 / 12 | All research grants and scholarships |
| Associated processes | |