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Sang Won Han

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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM)  (Institutional affiliation for the last research proposal)
Birthplace: Coréia do Sul

I graduated in Chemistry, Master and Doctorate in Biochemistry in the University of São Paulo, and was postdoctoral fellow in the University of Washington working on gene therapy. I was a professor of biochemistry in the Unesp between 1988-1996 and since 1996 I am a professor of Biophysics in the Escola Paulista de Medicina - Unifesp. Currently, I am a full professor of this university. I was co-founder of the Interdisciplinary center for Gene Therapy (CINTERGEN) in 2004 in the Unifesp, and had been director of this center since its foundation until 2010. The name CINTERGEN was changed to CTCMol. I am a member of the Technical Chamber of Advanced Therapies at ANVISA and representative of specialists at RENETA-ANVISA. Since 2019, I have been vice president of the Brazilian Association of Cell and Gene Therapy. The main research lines are: gene therapy of ischemic diseases, genetic diseases, cancer and DNA vaccine. Link to my Google Scholar is https://scholar.google.com.br/citations?user=j9dfSOEAAAAJ&hl=en (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
Scientists test gene therapy for mucopolysaccharidosis 
Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated April 17, 2021
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (30)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications25
Citations175
Cit./Article7.0
Data from Web of Science

SACRAMENTO, CHESTER BITTENCOURT; CANTAGALLI, VANESSA DIONISIO; GRINGS, MARIANA; CARVALHO, LEONARDO PINTO; COSTA BAPTISTA-SILVA, JOSE CARLOS; BEUTEL, ABRAM; BERGAMASCHI, CASSIA TOLEDO; DE CAMPOS JUNIOR, RUY RIBEIRO; DE MORAES, JANE ZVEITER; TAKIYA, CHRISTINA MAEDA; et al. Granulocyte-macrophage colony-stimulating factor gene based therapy for acute limb ischemia in a mouse model. JOURNAL OF GENE MEDICINE, v. 11, n. 4, p. 345-353, . Web of Science Citations: 11.

MCNEILL INGHAM, SHEILA JEAN; POCHINI, ALBERTO DE CASTRO; DE OLIVEIRA, DANIEL ANTONIO; GARCIA LISBOA, BIANCA CRISTINA; BEUTEL, ABRAM; VALERO-LAPCHIK, VALDEREZ BASTOS; FERREIRA, ANA MARIA; ABDALLA, RENE JORGE; COHEN, MOISES; HAN, SANG WON. Bupivacaine Injection Leads to Muscle Force Reduction and Histologic Changes in a Murine Model. PM&R, v. 3, n. 12, p. 1106-1109, . Web of Science Citations: 7. (11/00859-6)

MATSUMOTO MARTIN, PRISCILA KEIKO; STILHANO, ROBERTA SESSA; SAMOTO, VIVIAN YOCHIKO; TAKIYA, CHRISTINA MAEDA; PERES, GIOVANI BRAVIN; CORREA DA SILVA MICHELACCI, YARA MARIA; DA SILVA, FLAVIA HELENA; PEREIRA, VANESSA GONCALVES; D'ALMEIDA, VANIA; NAVARRO MARQUES, FABIO LUIZ; et al. Mesenchymal Stem Cells Do Not Prevent Antibody Responses against Human alpha-L-Iduronidase when Used to Treat Mucopolysaccharidosis Type I. PLoS One, v. 9, n. 3, . Web of Science Citations: 6. (08/56529-1, 09/52235-6, 08/56530-0)

CUNHA, FLAVIA FRANCO; MARTINS, LEONARDO; MATSUMOTO MARTIN, PRISCILA KEIKO; STILHANO, ROBERTA SESSA; HAN, SANG WON. A comparison of the reparative and angiogenic properties of mesenchymal stem cells derived from the bone marrow of BALB/c and C57/BL6 mice in a model of limb ischemia. STEM CELL RESEARCH & THERAPY, v. 4, . Web of Science Citations: 9. (11/00859-6)

STILHANO, ROBERTA SESSA; MATSUMOTO MARTIN, PRISCILA KEIKO; DE MELO, SUELY MAYMONE; SAMOTO, VIVIAN YOCHIKO; PERES, GIOVANI BRAVIN; CORREA DA SILVA MICHELACCI, YARA MARIA; DA SILVA, FLAVIA HELENA; PEREIRA, VANESSA GONCALVES; D'ALMEIDA, VANIA; DA CRUZ, ADRIANA TAVEIRA; et al. alpha-L-iduronidase gene-based therapy using the phiC31 system to treat mucopolysaccharidose type I mice. JOURNAL OF GENE MEDICINE, v. 17, n. 1-2, p. 1-13, . Web of Science Citations: 3. (09/52235-6)

MADRIGAL, JUSTIN L.; STILHANO, ROBERTA S.; SILTANEN, CHRISTIAN; TANAKA, KIMBERLY; REZVANI, SABAH N.; MORGAN, RYAN P.; REVZIN, ALEXANDER; HAN, SANG W.; SILVA, EDUARDO A.. Microfluidic generation of alginate microgels for the controlled delivery of lentivectors. JOURNAL OF MATERIALS CHEMISTRY B, v. 4, n. 43, p. 6989-6999, . Web of Science Citations: 10. (12/00753-6, 15/20206-8)

STILHANO, ROBERTA SESSA; SAMOTO, VIVIAN YOCHIKO; SILVA, LEONARDO MARTINS; PEREIRA, GUSTAVO JOSE; ERUSTES, ADOLFO GARCIA; SMAILI, SORAYA SOUBHI; HAN, SANG WON. Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor. PLoS One, v. 12, n. 10, . Web of Science Citations: 1. (12/00753-6, 15/20206-8)

TENG, YUAN-CHI; PORFIRIO-SOUSA, ALFREDO LEONARDO; RIBEIRO, GIULIA MAGRI; AREND, MARCELA CORSO; MEIRELLES, LINDOLFO DA SILVA; CHEN, ELIZABETH SUCHI; ROSA, DANIELA SANTORO; HAN, SANG WON. Analyses of the pericyte transcriptome in ischemic skeletal muscles. STEM CELL RESEARCH & THERAPY, v. 12, n. 1, . Web of Science Citations: 0. (17/17588-1, 15/20206-8)

MARTINS, LEONARDO; GALLO, CAMILA CONGENTINO; HONDA, TAMISA SEEKO BANDEIRA; ALVES, PATRICIA TERRA; STILHANO, ROBERTA SESSA; ROSA, DANIELA SANTORO; KOH, TIMOTHY JON; HAN, SANG WON. Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF. STEM CELL RESEARCH & THERAPY, v. 11, n. 1, . Web of Science Citations: 0. (16/04229-0, 11/15417-9, 18/09203-5)

MERTINS, OMAR; LOBO, SONJA ELLEN; MATHEWS, PATRICK D.; HAN, SANG WON. Interaction of pDNA with reverse phase chitosome. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, v. 543, p. 76-82, . Web of Science Citations: 0. (16/13368-4, 15/20206-8, 15/23948-5)

STILHANO, ROBERTA S.; MADRIGAL, JUSTIN L.; WONG, KEVIN; WILLIAMS, PRISCILLA A.; MARTIN, PRISCILA K. M.; YAMAGUCHI, FABIO S. M.; SAMOTO, VIVIAN Y.; HAN, SANG W.; SILVA, EDUARDO A.. Injectable alginate hydrogel for enhanced spatiotemporal control of lentivector delivery in murine skeletal muscle. JOURNAL OF CONTROLLED RELEASE, v. 237, p. 42-49, . Web of Science Citations: 17. (15/20206-8)

DE CARVALHO, BRUNA GREGATTI; TAKETA, THIAGO BEZERRA; MORENO GARCIA, BIANCA BONETTO; HAN, SANG WON; DE LA TORRE, LUCIMARA GAZIOLA. Hybrid microgels produced via droplet microfluidics for sustainable delivery of hydrophobic and hydrophilic model nanocarriers. Materials Science & Engineering C-Materials for Biological Applications, v. 118, . Web of Science Citations: 0. (18/19537-8, 15/20206-8, 18/18523-3)

MEIRELLES, LINDOLFO DA SILVA; MARSON, RENAN FAVA; GONZALEZ SOLARI, MARIA INES; NARDI, NANCE BEYER. Are Liver Pericytes Just Precursors of Myofibroblasts in Hepatic Diseases? Insights from the Crosstalk between Perivascular and Inflammatory Cells in Liver Injury and Repair. CELLS, v. 9, n. 1, . Web of Science Citations: 0. (15/20206-8)

DE CARVALHO‚ L.P.; TAKESHITA‚ D.; CARILLO‚ B.A.; LISBÔA‚ B.C.G.; MOLINA‚ G.; BEUTEL‚ A.; YASUMURA‚ E.G.; TAKIYA‚ C.M.; VALERO‚ V.B.; DE CAMPOS‚ JR‚ R.R.; et al. Hydrodynamics-and ultrasound-based transfection of heart with naked plasmid DNA. Human Gene Therapy, v. 18, n. 12, p. 1233-1243, .

SACRAMENTO, C. B.; MORAES, J. Z.; DENAPOLIS, P. M. A.; HAN, S. W.. Gene expression promoted by the SV40 DNA targeting sequence and the hypoxia-responsive element under normoxia and hypoxia. Brazilian Journal of Medical and Biological Research, v. 43, n. 8, p. 722-727, . Web of Science Citations: 12.

YASUMURA, EDUARDO GALLATTI; STILHANO, ROBERTA SESSA; SAMOTO, VIVIAN YOCHIKO; MATSUMOTO, PRISCILA KEIKO; DE CARVALHO, LEONARDO PINTO; VALERO LAPCHIK, VALDEREZ BASTOS; HAN, SANG WON. Treatment of Mouse Limb Ischemia with an Integrative Hypoxia-Responsive Vector Expressing the Vascular Endothelial Growth Factor Gene. PLoS One, v. 7, n. 3, p. e33944, . Web of Science Citations: 9. (11/00859-6)

BENTES DE PAULA, DAISY MARIA; VALERO-LAPCHIK, VALDEREZ BASTOS; PAREDES-GAMERO, EDGAR JULIAN; HAN, SANG WON. Therapeutic ultrasound promotes plasmid DNA uptake by clathrin-mediated endocytosis. JOURNAL OF GENE MEDICINE, v. 13, n. 7-8, p. 392-401, . Web of Science Citations: 28.

CHOUDHURI, JOMUNA V.; MATHOR, MONICA B.; SILVA, FLAVIA H.; HAN, SANG W.. Autonomous growth of BALB/MK keratinocytes transfected with a retroviral vector carrying the human epidermal growth factor gene. GENETICS AND MOLECULAR BIOLOGY, v. 31, n. 4, p. 824-828, . Web of Science Citations: 2.

ROSEGUINI, BRUNO T.; SILVA, LEONARDO M.; POLOTOW, TATIANA G.; BARROS, MARCELO P.; SOUCCAR, CADEN; HAN, SANG W.. Effects of N-acetylcysteine on skeletal muscle structure and function in a mouse model of peripheral arterial insufficiency. JOURNAL OF VASCULAR SURGERY, v. 61, n. 3, p. 777-786, . Web of Science Citations: 7. (10/51344-3, 11/18197-0, 11/00859-6)

BENTO‚ F.; TAKESHITA‚ D.; SACRAMENTO‚ C.; MACHADO‚ T.; MATHOR‚ M.; CARMONA‚ A.; HAN‚ S.. Over expression of the selectable marker blasticidin S deaminase gene is toxic to human keratinocytes and murine BALB/MK cells. BMC Biotechnology, v. 4, n. 1, p. 29, .

DENAPOLI, PRISCILA M. A.; ZANETTI, BIANCA F.; DOS SANTOS, ADARA A.; DE MORAES, JANE Z.; HAN, SANG W.. Preventive DNA vaccination against CEA-expressing tumors with anti-idiotypic scFv6.C4 DNA in CEA-expressing transgenic mice. CANCER IMMUNOLOGY IMMUNOTHERAPY, v. 66, n. 3, p. 333-342, . Web of Science Citations: 3. (12/21861-1)

DE MELO, SUELY MAYMONE; BITTENCOURT, SIMONE; FERRAZOLI, ENEAS GALDINI; DA SILVA, CLIVANDIR SEVERINO; DA CUNHA, FLAVIA FRANCO; DA SILVA, FLAVIA HELENA; STILHANO, ROBERTA SESSA; ANDRADE DENAPOLI, PRISCILA MARTINS; ZANETTI, BIANCA FERRARINI; MATSUMOTO MARTIN, PRISCILA KEIKO; et al. The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor. PLoS One, v. 10, n. 6, . Web of Science Citations: 26. (12/21861-1)

MARTINS, GRAZIELI OLINDA; PETRONIO, MAICON SEGALLA; FURUYAMA LIMA, ALINE MARGARETE; MARTINEZ JUNIOR, ANDRE MIGUEL; DE OLIVEIRA TIERA, VERA APARECIDA; CALMON, MARILIA DE FREITAS; LEITE VILAMAIOR, PATRICIA SIMONE; HAN, SANG WON; TIERA, MARCIO JOSE. Amphipathic chitosans improve the physicochemical properties of siRNA-chitosan nanoparticles at physiological conditions. Carbohydrate Polymers, v. 216, p. 332-342, . Web of Science Citations: 3. (17/10331-5, 12/24259-0, 15/05148-1, 15/20206-8)

SHELDON, RYAN D.; ROSEGUINI, BRUNO T.; LAUGHLIN, M. HAROLD; NEWCOMER, SEAN C.. New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease. JOURNAL OF VASCULAR SURGERY, v. 58, n. 6, p. 1688-1696, . Web of Science Citations: 10. (11/18197-0)

DA CUNHA, FLAVIA FRANCO; MARTINS, LEONARDO; MATSUMOTO MARTIN, PRISCILA KEIKO; STILHANO, ROBERTA SESSA; PAREDES GAMERO, EDGAR JULIAN; HAN, SANG WON. Comparison of treatments of peripheral arterial disease with mesenchymal stromal cells and mesenchymal stromal cells modified with granulocyte and macrophage colony-stimulating factor. CYTOTHERAPY, v. 15, n. 7, p. 820-829, . Web of Science Citations: 10. (11/00859-6)

DE MELLO, LUCAS RODRIGUES; HAMLEY, IAN WILLIAM; CASTELLETTO, VALERIA; MORENO GARCI, BIANCA BONETTO; HAN, SANG WON; PINTO DE OLIVEIRA, CRISTIANO LUIS; DA SILV, EMERSON RODRIGO A. Nanoscopic Structure of Complexes Formed between DNA and the Cell-Penetrating Peptide Penetratin. Journal of Physical Chemistry B, v. 123, n. 42, p. 8861-8871, . Web of Science Citations: 0. (15/20206-8, 16/24409-3)

ZANETTI, BIANCA FERRARINI; FERREIRA, CAMILA PONTES; CARVALHO DE VASCONCELOS, JOSE RONNIE; HAN, SANG WON. scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor. Gene Therapy, v. 26, n. 10-11, p. 441-454, . Web of Science Citations: 0. (13/17224-9, 12/21861-1)

CARVALHO, BRUNA G.; VIT, FRANCIELE F.; CARVALHO, HERNANDES F.; HAN, SANG W.; DE LA TORRE, LUCIMARA G.. Recent advances in co-delivery nanosystems for synergistic action in cancer treatment. JOURNAL OF MATERIALS CHEMISTRY B, v. 9, n. 5, p. 1208-1237, . Web of Science Citations: 1. (18/18523-3, 15/20206-8, 18/19537-8)

SANG WON HAN; CARLOS ALBERTO VERGANI JUNIOR; PAULO EDUARDO OCKE REIS. Terapia gênica de isquemia de membro é uma realidade?. Jornal Vascular Brasileiro, v. 19, p. -, . (15/20206-8)

GARCIA, BIANCA B. M.; MERTINS, OMAR; DA SILVA, EMERSON R.; MATHEWS, PATRICK D.; HAN, SANG W.. Arginine-modified chitosan complexed with liposome systems for plasmid DNA delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 193, . Web of Science Citations: 1. (15/20206-8, 15/23948-5, 16/13368-4)

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