Carla Roberta de Oliveira Carvalho

• Abstract

  The strategic action plan to tackle chronic diseases highlights diabetes as one of the main diseases that led to the Brazilian economic loss of US $ 4.18 billion between the years 2006 to 2015. Currently, one of the surgical treatments available for obesity is being studied as an option for the treatment of diabetes due to its post-operative effects in the face of rapid and intense improv…

  Kombucha and its interaction between bile acids, gut microbiota composition and intestinal inflammatory state, AP.R

• Abstract

  Obesity and overweight are major risk factors for non-communicable chronic diseases such as diabetes, cardiovascular disease, non-alcoholic fatty liver disease and some types of cancers. With the progression of overweight to obesity there is an aseptic inflammatory condition starting up on white adipose tissue. In this regard, there is activation of JNK/IKK² intracellular pathways, which …

  Uncaria tomentosa effect on peripheral insulin sensitivity, and intestinal microflora barrier in C57BL / 6 mice, AP.R

• Abstract

  Metabolic and immune systems are among the basic requirements for survival and interaction between them is decisive to the health and survival of the organism. Obesity and its metabolic disorders, such as insulin resistance and diabetes, are associated with inflammatory conditions and are currently being associated with changes in intestinal flora. The role of new drugs such as antibioti…

  Effect of Liraglutide and Bauhinia variegata (L.) on the gut microbiota of C57BL6 mice and ob/ob, AP.R

(Only some records are available in English at this moment)

• Abstract

  Obesity and overweight are major risk factors for non-communicable chronic diseases such as diabetes, cardiovascular disease, non-alcoholic fatty liver disease and some types of cancers. With the progression of overweight to obesity there is an aseptic inflammatory condition starting up on white adipose tissue. In this regard, there is activation of JNK/IKK² intracellular pathways, which …

  Effect of Uncaria tomentosa in accumulation of intracellular fat in HepG2 cells induced with oleic and / or palmitic fatty acids, BP.IC

• Abstract

  The discovery of new drugs usually is an expensive and long process, because it involves the development of new chemical bioactive compounds with desirable biological functions and minimal side effects. Considering insulin resistance and type 2 diabetes (DM2) as polymorphic metabolic and multifactorial disturbances, but unknown inflammatory origins, one could ask the effectiveness that he…

  EFFECT OF Uncaria tomentosa AND Harpagophytum procumbens IN THE INTERRELATION BETWEEN INFLAMMATION, INSULIN RESISTANCE AND TYPE 2 DIABETES, BP.PD

• Abstract

  Deprivation sex hormones, natural or induced, contributes to the appearance of several metabolic and endocrine disorders such as insulin resistance, glucose intolerance and diabetes, and cardiovascular diseases, due in part to the protective effect of estrogens. Dehydroepiandrosterone (DHEA), most abundant steroid in humans, produce primarily by the adrenal cortex, is converted to androge…

  Effect of supplementation with DHEA in the heart of rats with hypertension induced by castration and high fat diet, BP.MS

(Only some records are available in English at this moment)

• Abstract

  Our research group has being studying the modulation events of melatonin synthesis by peptidergic systems as insulin and leptin, as well as the actions of melatonin as a zeitgeber (time-keeper) to the heart. We have shown that insulin potentiates melatonin synthesis in the pineal gland due to an increase in the activities of the main enzymes involved on the synthesis of the pineal hormone…

  Cardiomyocytes circadian clock in adaptation of the heart to STZ-induced diabetes mellitus, BE.EP.PD