CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Odontologia from Faculdade de Odontologia de Piracicaba-UNICAMP (2001), master's at Odontologia from Faculdade de Odontologia de Piracicaba-UNICAMP (2004) and doctorate at Odontologia from Faculdade de Odontologia de Piracicaba-UNICAMP (2008). Has experience in Biochemistry, focusing on Biochemetry of the Microorganisms, acting on the following subjects: starch, dentine, biofilm, sucrose and bioethics. (Source: Lattes Curriculum)
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Dental caries is a biofilm-sugar dependent disease that destroys mineralized dental tissues. Its control should focus on a balanced diet and disorganization of the biofilm by daily brushing with dentifrices, which can be vehicles for active substances such as antimicrobials, aiming at controlling the cariogenic biofilm. However, the effect of these actives on the innermost portions of the…
A polysaccharide extracted from mango (Mangifera indica L.) has been suggested as a new alternative for the induction of glucanase in Trichoderma harzianum. Glucanase can degrade glucans, the main constituent of cariogenic biofilms, such as those produced by Streptococcus mutans. Mango is one of the most consumed fruits in Brazil and its processing in the food industry is capable of gener…
Diseases caused by biofilms are a major public health problem, being responsible for the increased morbidity of patients and the hospital stay and healthcare costs. Among the biofilm-dependent diseases most studied today are the urinary tract and oral diseases. Thus, the broadcasting of drugs that might have prolonged effect in a pharmaceutical formulation of controlled release can be ver…
Biolfim is the etiologic factor for most oral diseases such as caries, gingivitis and periodontitis. Thus, the control of biofilm can help to decrease such diseases. A number of studies have been conducted in order to develop products containing antimicrobials that can interfere on this mechanism. In this sense, controlled drug delivery systems (DDS) have been developed to be used in the …
(Only some records are available in English at this moment)
Dental caries is a biofilm-sugar dependent disease that destroys mineralized dental tissues. Its control should focus on a balanced diet and disorganization of the biofilm by daily brushing with dentifrices, which can be vehicles for active substances such as antimicrobials, aiming at controlling the cariogenic biofilm. However, the effect of these actives on the innermost portions of the…
The control of oral biofilm in children represents a challenge for Pediatric Dentistry. Considering that, this work aims to isolate polysaccharides from the industrial residues of mango (peel, seed kernel, and seed) and evaluate its potential as an enzyme inducer in Trichoderma harzianum, studying the effect of glucanases produced on cariogenic biofilm. This work will occur in two stages.…
Biofilm control in individuals with orthodontic needs is considered a real challenge in Dentistry and can have serious implications on the patient's oral health. Orthodontic device is indicated for cases of transverse maxillary disharmony, a condition commonly found in young patients. However, the use of this device is recommended for a prolonged period (6 months), which could cause diffi…
Considering that bacterial intracellular polysaccharides (IPS) may be an important factor for the development of dental caries with associated methodological limitations in their extraction, the objective of the study is to evaluate the effect of different extraction protocols on streptococcus mutans IPS. Thus, biofilms of S. mutans UA 159 will be formed for 5 days on glass slide placed i…
(Only some records are available in English at this moment)
Dental caries is a sugar-mediated microbial dysbiosis in which extracellular polymeric substances (EPS) play a crucial role in biofilm formation and virulence. Mutans streptococci, a member of the oral microbiome, produce water-soluble (dextran) and insoluble (mutan) glucans from dietary sugars such as sucrose. These glucans form an extracellular matrix that promotes biofilm accumulation …
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 12 / 8 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 20 / 16 | All research grants and scholarships |
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