CV Lattes
Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Química Industrial from Universidade de Franca (2008), master's at Programa de Pós-Graduação em Ciências - Universidade de Franca from Universidade de Franca (2011) and doctorate at Pharmacy from Universidade de São Paulo (2015). (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Cruzain, the main cysteine protease of Trypanosoma cruzi, is an essential enzyme for the life cycle of the parasite and has been used as a viable target for searching for enzyme inhibitors as drug candidates. The peptide mimetic compound K11777 inhibits cruzain at nanomolar concentrations, and acts by an irreversible inhibition mechanism. Analogs or derivatives K11777 usually contain elec…
The objective of this project is the development of organometallic reagents for biological active molecules synthesis. In the first part of the work a number of bases such as TMPLi, TMPMgCl.LiCl, TMPZnCl.LiCl e TMP2Mg.2LiCl will be prepared and used in the functionalization of dioxinones. Aiming to develop more stable and selective bases, in the second part of the work some new bases deri…
| 3 / 2 | Completed scholarships in Brazil |
| Associated processes | |