| 2 / 2 | Ongoing grants |
| 3 / 3 | Completed research grants |
| 8 / 8 | Ongoing scholarships in Brazil |
| 15 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 30 / 30 | All research grants and scholarships |
| Associated processes | |
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João Agostinho Machado Neto
CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. João Agostinho Machado-Neto graduated in Biology from the CEUSNP in 2009 and earned a Master's degree in Clinical Medicine from the University of Campinas (Unicamp) in 2011, where he also completed his Ph.D. in Sciences, focusing on Clinical Medicine, in 2015. He then pursued postdoctoral research at the Ribeirão Preto Medical School of the University of São Paulo (FMRP - USP-RP) from 2015 to 2017, with a focus on studying cellular signaling pathways in cancer. Currently, he is an Associate Professor in the Department of Pharmacology at the Institute of Biomedical Sciences, University of São Paulo (ICB - USP). His research focuses on the identification and characterization of antineoplastic compounds and the investigation of the expression, activation, and function of genes involved in altered cellular signaling pathways in cancer, with a particular emphasis on hematological malignancies. His work aims to deeply understand the molecular mechanisms contributing to cancer development and to explore new therapeutic strategies that could have a direct impact on the treatment of these diseases. (Source: Lattes Curriculum)
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Research grants
- Investigation of the antineoplastic effects of novel PIP4K2 and HDAC inhibitors in hematologic malignancies, AP.R
- Comprehensive analysis of genomic data for identification and validation of novel therapeutic targets involved in cellular cytoskeleton regulation in acute Leukemia, AP.R
- Investigation of Stathmin 1 and microtubule instability in phenotype of hematological neoplasms, AP.R
Scholarships in Brazil
- Exploiting mitochondrial genome expression as a therapeutic vulnerability in acute myeloid leukemia, BP.PD
- Investigation of the impact of mutations in the TP53 gene on clinical outcome and the interaction of the p53 protein with the drug APR-246 in acute myeloid leukemia, BP.DR
- Investigation of the prognostic impact of PIP4K2s and their pharmacological inhibition in hepatocellular carcinoma, BP.DD
(Only some records are available in English at this moment)
- Investigation of potential molecular targets in models of acute myeloid leukemias with acquired resistance to venetoclax., BP.MS
- Investigation of the antineoplastic potential of pharmacological inhibition of ezrin in solid tumors: gastric adenocarcinoma and cervical carcinoma, BP.IC
- Investigation of the effects of the multikinase inhibitor AD80 in hematological neoplasms with constitutive activation of tyrosine kinase pathways, BP.DD
(Only some records are available in English at this moment)
Scholarships abroad
Total / Available in English
- Lívia Bassani Lins de Miranda
- Sara Teresinha Olalla Saad
- Fabíola Traina
- Hugo Passos Vicari
- Jorge Antonio Elias Godoy Carlos
- Jean Carlos Lipreri da Silva
- Bruna Oliveira de Almeida
- Natália Sudan Parducci
- Maria Fernanda Lopes Carvalho
- Camila Yumi Soares Hirakata
- Gustavo Nery de Queiroz
- Isabelle Diccini