CV Lattes
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Universidade São Francisco (USF). Campus Bragança Paulista (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas from Pontifícia Universidade Católica de Campinas (1998), master's at Clinical Medicine from Universidade Estadual de Campinas (2001) and ph.d. at Pharmacology from Universidade Estadual de Campinas (2004). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: helicobacter pylori, gastric cancer and DNA repair; obesity and adipogenesis (Source: Lattes Curriculum)
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Gastric cancer remains one of the leading causes of global cancer mortality. It has been shown that gastric cancer may originate from adult gastric stem cells and that it contains a subpopulation of cancer cells with stem cell characteristics, which are linked to Helicobacter pylori infection, therapy resistance and metastasis. Thus, the identification of transcription factors and related…
It is known that H. pylori infection triggers a pathological progression in the gastric mucosa which eventually culminates in the development of gastric cancer. Inevitably, the infection causes an inflammatory response in the host, which generates reactive oxygen species and nitrogen, which can cause protein alterations, damage to cell membranes and oxidation of the DNA molecule, which ar…
It has been hypothesised that genetic variation in base excision repair (BER) might modify colorectal adenoma risk. Thus, we evaluated the influence of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1, and OGG1 expression in normal and tumour samples from patients with colorectal cancer. The results indicate a down-regulation of OGG1 and an up-regulation of XRCC1 expression in t…
(Only some records are available in English at this moment)
It is known that H. pylori infection triggers a pathological progression in gastric mucosa, which eventually culminates in the development of gastric cancer. Inevitably, the infection causes an inflammatory response in the host, which generates reactive oxygen species and nitrogen, which may cause protein alterations, damage to cell membranes and oxidation DNA molecule, which are known to…
It is known that H. pylori infection triggers a pathological progression in gastric mucosa which eventually culminates in the development of gastric cancer. Inevitably, the infection causes an inflammatory response in the host, which generates reactive species of oxygen and nitrogen, which can cause protein alterations, damage to cell membranes and oxidation to the DNA molecule, which are…
It is now known that gastric cancer is primarily a disease with an epigenetic origin. It has been shown that infection by H. pylori triggers a pathological progression in gastric mucosa that starts with chronic gastritis progresses to atrophic gastritis, intestinal metaplasia, dysplasia and eventually gastric cancer. It is believed that the inflammatory response generated by the infection…
(Only some records are available in English at this moment)
| 11 / 9 | Completed research grants |
| 16 / 9 | Completed scholarships in Brazil |
| 27 / 18 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 14 |
| Citations | 339 |
| Cit./Article | 24.2 |
| Data from Web of Science | |
ARCARI, DEMETRIUS P.; BARTCHEWSKY, WALDEMAR; DOS SANTOS, TANILA W.; OLIVEIRA, KARIM A.; FUNCK, ALEXANDRE; PEDRAZZOLI, JOSE; DE SOUZA, MARINA F. F.; SAAD, MARIO J.; BASTOS, DEBORAH H. M.; GAMBERO, ALESSANDRA; et al. Antiobesity Effects of yerba mate Extract (Ilex paraguariensis) in High-fat Diet-induced Obese Mice. OBESITY, v. 17, n. 12, p. 2127-2133, DEC 2009. Web of Science Citations: 94.
BARTCHEWSKY, JR., WALDEMAR; MARTINI, MARIANA R.; SQUASSONI, ALINE C.; ALVAREZ, MARISA C.; LADEIRA, MARCELO S. P.; SALVATORE, DAISY M. F.; TREVISAN, MIRIAM A.; PEDRAZZOLI, JR., JOSE; RIBEIRO, MARCELO L.. Effects of Helicobacter pylori Infection on the Expressions of Bax and Bcl-2 in Patients with Chronic Gastritis and Gastric Cancer. Digestive Diseases and Sciences, v. 55, n. 1, p. 111-116, JAN 2010. Web of Science Citations: 13.
FERREIRA, LIVIA ROSAS; MACEDO, JULIANA ALVES; RIBEIRO, MARCELO LIMA; MACEDO, GABRIELA ALVES. Improving the chemopreventive potential of orange juice by enzymatic biotransformation. Food Research International, v. 51, n. 2, p. 526-535, MAY 2013. Web of Science Citations: 21. (09/07821-4)
ARCARI, DEMETRIUS P.; BARTCHEWSKY, JR., WALDEMAR; DOS SANTOS, TANILA W.; OLIVEIRA, KARIM A.; DEOLIVEIRA, CARLORINE C.; GOTARDO, ERICA M.; PEDRAZZOLI, JR., JOSE; GAMBERO, ALESSANDRA; FERRAZ, LUCIO F. C.; CARVALHO, PATRICIA DE O.; et al. Anti-inflammatory effects of yerba mate extract (Ilex paraguariensis) ameliorate insulin resistance in mice with high fat diet-induced obesity. Molecular and Cellular Endocrinology, v. 335, n. 2, p. 110-115, MAR 30 2011. Web of Science Citations: 58.
BARTCHEWSKY, JR., W.; MARTINI, M. R.; SQUASSONI, A. C.; ALVAREZ, M. C.; LADEIRA, M. S. P.; SALVATORE, D. M. F.; TREVISAN, M. A.; PEDRAZZOLI, JR., J.; RIBEIRO, M. L.. Influence of Helicobacter pylori infection on the expression of MLH1 and MGMT in patients with chronic gastritis and gastric cancer. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, v. 28, n. 6, p. 591-597, JUN 2009. Web of Science Citations: 4.
SANTOS, JULIANA C.; GAMBELONI, RAFAEL Z.; ROQUE, ALINE T.; OECK, SEBASTIAN; RIBEIRO, MARCELO L.. Epigenetic Mechanisms of ATM Activation after Helicobacter pylori Infection. American Journal of Pathology, v. 188, n. 2, p. 329-335, FEB 2018. Web of Science Citations: 1. (14/11862-6, 15/08775-7, 11/21710-0, 15/17768-4)
MACEDO, J. A.; FERREIRA, L. R.; CAMARA, L. E.; SANTOS, J. C.; GAMBERO, A.; MACEDO, G. A.; RIBEIRO, M. L.. Chemopreventive potential of the tannase-mediated biotransformation of green tea. Food Chemistry, v. 133, n. 2, p. 358-365, JUL 15 2012. Web of Science Citations: 16. (09/07821-4)
ALVAREZ, MARISA C.; SANTOS, JULIANA C.; MANIEZZO, NATHALIA; LADEIRA, MARCELO S.; DA SILVA, ARTUR L. C.; SCALETSKY, ISABEL C. A.; PEDRAZZOLI, JR., JOSE; RIBEIRO, MARCELO L.. MGMT and MLH1 methylation in Helicobacter pylori-infected children and adults. WORLD JOURNAL OF GASTROENTEROLOGY, v. 19, n. 20, p. 3043-3051, MAY 28 2013. Web of Science Citations: 25. (09/01813-0, 08/02678-6)
SANTOS, J. C.; LADEIRA, M. S. P.; PEDRAZZOLI, JR., J.; RIBEIRO, M. L.. Relationship of IL-1 and TNF-alpha polymorphisms with Helicobacter pylori in gastric diseases in a Brazilian population. Brazilian Journal of Medical and Biological Research, v. 45, n. 9, p. 811-817, SEP 2012. Web of Science Citations: 33.
SANTOS, JULIANA C.; BRIANTI, MITSUE T.; ALMEIDA, VICTOR R.; ORTEGA, MANOELA M.; FISCHER, WOLFGANG; HAAS, RAINER; MATHEU, ANDER; RIBEIRO, MARCELO L.. Helicobacter pylori Infection Modulates the Expression of miRNAs Associated With DNA Mismatch Repair Pathway. Molecular Carcinogenesis, v. 56, n. 4, p. 1372-1379, APR 2017. Web of Science Citations: 14. (14/11862-6)
CARRASCO-GARCIA, ESTEFANIA; SANTOS, JULIANA C.; GARCIA, IDOIA; BRIANTI, MITSUE; GARCIA-PUGA, MIKEL; JR PEDRAZZOLI, JOSE; MATHEU, ANDER; RIBEIRO, MARCELO L.. Paradoxical role of SOX2 in gastric cancer. AMERICAN JOURNAL OF CANCER RESEARCH, v. 6, n. 4, p. 701-713, 2016. Web of Science Citations: 16. (14/11862-6, 11/21710-0)
MIRANDA‚ D.D.C.; ARÇARI‚ D.P.; PEDRAZZOLI JR‚ J.; CARVALHO‚ P.O.; CERUTTI‚ S.M.; BASTOS‚ D.H.M.; RIBEIRO‚ M.L.. Protective effects of mate tea (Ilex paraguariensis) on H2O2-induced DNA damage and DNA repair in mice. MUTAGENESIS, v. 23, n. 4, p. 261-265, 2008.
SANTOS, JULIANA CARVALHO; CARRASCO-GARCIA, ESTEFANIA; GARCIA-PUGA, MIKEL; ALDAZ, PAULA; MONTES, MILAGROSA; FERNANDEZ-REYES, MARIA; DE OLIVEIRA, CAROLINE CANDIDA; LAWRIE, CHARLES H.; ARAUZO-BRAVO, MARCOS J.; RIBEIRO, MARCELO LIMA; et al. SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression. Cancer Research, v. 76, n. 22, p. 6735-6746, NOV 15 2016. Web of Science Citations: 31. (14/11862-6)
ALVAREZ, MARISA CLAUDIA; FERNANDES, JULIEN; MICHEL, VALERIE; TOUATI, ELIETTE; RIBEIRO, MARCELO LIMA. Effect of Helicobacter pylori Infection on GATA-5 and TFF1 Regulation, Comparison Between Pediatric and Adult Patients. Digestive Diseases and Sciences, v. 63, n. 11, p. 2889-2897, NOV 2018. Web of Science Citations: 3. (08/02678-6, 11/11224-1)
ALVAREZ, MARISA CLAUDIA; PLACIDO LADEIRA, MARCELO SADY; AFFONSO SCALETSKY, ISABEL CRISTINA; PEDRAZZOLI, JR., JOSE; RIBEIRO, MARCELO LIMA. Methylation Pattern of THBS1, GATA-4, and HIC1 in Pediatric and Adult Patients Infected with Helicobacter pylori. Digestive Diseases and Sciences, v. 58, n. 10, p. 2850-2857, OCT 2013. Web of Science Citations: 10. (08/02678-6)
(References retrieved automatically from State of São Paulo Research Institutions)
PRAX, Marisa Claudia Alvarez de. Análise da influência da infecção por Helicobacter pylori no padrão de metilação de genes envolvidos na carcinogênese gástrica. Tese (Doutorado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). (08/02678-6)
SANTOS, Juliana Carvalho. Determinação do perfil epigenético relacionado aos sistemas de reparo ao DNA influenciados pela infecção por "Helicobacter pylori" = Evaluation of epigenetic profile associated with DNA repair systems induced by "Helicobacter pylori". Tese (Doutorado) - Instituto de Biologia. Universidade Estadual de Campinas. (11/21710-0)
RIBEIRO, Marcelo Lima. Distribuição dos polimorfismos dos genes do receptor de androgenos e da 5-alfa Redutase tipo II relacionados ao cancer de prostata em uma amostra da população masculina do estado de São Paulo. Dissertação (Mestrado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas (UNICAMP). (99/04512-7)