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Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Luiz Fernando Toneto Novaes in research grants and scholarships supported by FAPESP.
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The project proposes a simplification of synthesis of dioxiranes, and the use in C-H oxidations under continuous flow conditions. We also propose the total synthesis and structural elucidation of meroterpenoid actinoranone. Furthermore, we intend to explore the synthesis of the decalin fragment of azadirachtin by a bioinspired approach: from the terpene sclareolide would be performed eigh…
This research proposal aims the synthesis of tarchonanthuslactone, a natural product isolated from the leaves of the tree Tarchonanthus trilobus, whose biological activity has not yet been explored. The sructure of tarchonanthuslactone may be envisioned as a hybrid structure of cafeic acid, a natural product isolated from the fruit of Xanthium strumarium which has inhibitory activity of p…
This project refers to the exploration of synthetic methods for the transformation of lactose, an abundant natural disaccharide, in bicyclic lactones systems with furanofurone and furanopirone skeletons. These molecules present a great interest for biological activity studies, especially due to their structural similarity with other bicycles with known cytotoxic action, as exemplified by…
The rise of pathogenic bacteria resistant to known antibiotics is a growing concern with potentially catastrophic consequences as recently noted by The Center for Disease Control. Antibiotic-resistant hospital acquired infections claim over 23,000 lives and cause greater than 2 million illnesses in the United States alone each year. The direct health care costs of such infections have be…
The present project aims to study the Hetero Diels-Alder reaction (HDA), as a tool to construct alfa, beta-unsaturated delta-lactones, an important structural moiety present in natural products such as goniothalamin and fostriecin which display biological activity against cancer. We plan to study two asymmetric HDA methods, one based on the Jacobsen's catalyst, the other using Lewis acids…
| 3 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
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