graduation at Biomedicina from Universidade de Franca (2004), master's at Genetics from Universidade Estadual de Londrina (2007) and doctorate at Pharmacy from Universidade de São Paulo (2011). Has experience in Pharmacology, focusing on Toxicology, acting on the following subjects: metilmercúrio, antigenotoxicidade, polimorfismos, v79 and genotoxicidade. (Source: Lattes Curriculum)
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Epidemiological studies showed that exposure to mercury (Hg), especially to methylmercury (MeHg), is associated with changes in biochemical parameters associated with nutritional status, with disturbances in the cellular redox state, leading to oxidative damage of macromolecules, such as lipids, proteins and DNA; in addition, recent studies suggest that metal exposure is also associated w…
Epidemiological studies demonstrate that mercury (Hg), especially methylmercury (MeHg), can induce oxidative stress, systemic inflammation and DNA damage; in addition, recent studies suggest that exposure to metal is also related to changes in epigenetic status. However, there is still a gap regarding how exposure to Hg may impact the expression of genes related to the DNA methylation pro…
Triclosan (TCS) is an antimicrobial agent widely used in personal hygiene products (PHP) and diethylhydroxyl (DEHP) is a phthalate group of chemical compounds derived from phthalic acid and is used in medical equipment and plastic products with chlorinated polyvinyls. As a result of their extensive use, these toxicants have been found in the environment and previous studies have demonstra…
There is a wide variation in concentrations of the biomarkers of exposure, effect, and susceptibility associated with exposure to toxic metals despite similar levels of exposure and this is hypothetically related gene modulation in the process kinetics and dynamics of these metals. However, very little is known about the genome effects on the metabolism and toxicity induced by exposure to…
Epidemiological studies show that mercury (Hg), especially methylmercury (MeHg), can induce oxidative stress, systemic inflammation and DNA damage; in addition, recent studies suggest that exposure to metal is also related to changes in epigenetic status. However, there is still a gap regarding how exposure to Hg can impact the expression of genes related to the DNA methylation profile an…
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Studies suggest that exposure to toxic metals, such as lead (Pb) may induce various epigenetic changes, such as changes in DNA methylation profile, chromatin remodeling, as well as the expression of non-coding RNAs (ncRNAs), among them micro RNAs (miRNAs). Several miRNAs are being detected and related to metal exposure; however, there are still many differences in the expression profiles …
Mercury (Hg) is one of the most toxic metals in the environment, causing many adverse health effects. Its elimination is done by slowly conjunction with glutathione (GSH) through a detoxification system that involves several steps with this compound. Thus, the hypothesis being examined in this project is that the genetic polymorphism related to the enzyme-glutamyl-cysteine-ligase M (GCLM-…
| 1 / 1 | Ongoing grants |
| 3 / 3 | Completed research grants |
| 12 / 11 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 18 / 17 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID