CV Lattes
ORCID
Google Scholar Citations
Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Instituto de Saúde e Sociedade (ISS) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Biomedicina from Universidade de Franca (2004), master's at Genetics from Universidade Estadual de Londrina (2007) and doctorate at Pharmacy from Universidade de São Paulo (2011). Has experience in Pharmacology, focusing on Toxicology, acting on the following subjects: metilmercúrio, antigenotoxicidade, polimorfismos, v79 and genotoxicidade. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Epidemiological studies showed that exposure to mercury (Hg), especially to methylmercury (MeHg), is associated with changes in biochemical parameters associated with nutritional status, with disturbances in the cellular redox state, leading to oxidative damage of macromolecules, such as lipids, proteins and DNA; in addition, recent studies suggest that metal exposure is also associated w…
Epidemiological studies demonstrate that mercury (Hg), especially methylmercury (MeHg), can induce oxidative stress, systemic inflammation and DNA damage; in addition, recent studies suggest that exposure to metal is also related to changes in epigenetic status. However, there is still a gap regarding how exposure to Hg may impact the expression of genes related to the DNA methylation pro…
Triclosan (TCS) is an antimicrobial agent widely used in personal hygiene products (PHP) and diethylhydroxyl (DEHP) is a phthalate group of chemical compounds derived from phthalic acid and is used in medical equipment and plastic products with chlorinated polyvinyls. As a result of their extensive use, these toxicants have been found in the environment and previous studies have demonstra…
There is a wide variation in concentrations of the biomarkers of exposure, effect, and susceptibility associated with exposure to toxic metals despite similar levels of exposure and this is hypothetically related gene modulation in the process kinetics and dynamics of these metals. However, very little is known about the genome effects on the metabolism and toxicity induced by exposure to…
Epidemiological evidence has shown that Hg causes disturbances in the redox status, leading to oxidative and DNA damage. However, no studies have been conducted to evaluate the impact of metal exposure on the expression of genes associated with DNA damage signaling pathway as well as the possible influences of genetic polymorphisms of the DNA repair system on the genotoxicity induced by t…
Epidemiological studies show that mercury (Hg), especially methylmercury (MeHg), can induce oxidative stress, systemic inflammation and DNA damage; in addition, recent studies suggest that exposure to metal is also related to changes in epigenetic status. However, there is still a gap regarding how exposure to Hg can impact the expression of genes related to the DNA methylation profile an…
Lead (Pb) is a toxic metal widely used as a raw material in the industry for the manufacture of rubber, glazes, glass and especially in automotive battery factories where workers are exposed to metal. Due to its potential to produce free radicals and reactive species, Pb can cause damage to the DNA, which, if not correctly repaired, generates cytogenetic damage, such as micronuclei (MNs) …
There are wide variations in the concentrations of the biomarkers and toxicity related to lead (Pb), despite similar levels of exposure and this is hypothetically related genetic differences in the enzymes that metabolize metal. However, very little is known about the genetic effects on metabolism and toxicity induced by Pb. Therefore, this project aims to assess the gene-metal interactio…
(Only some records are available in English at this moment)
Studies suggest that exposure to toxic metals, such as lead (Pb) may induce various epigenetic changes, such as changes in DNA methylation profile, chromatin remodeling, as well as the expression of non-coding RNAs (ncRNAs), among them micro RNAs (miRNAs). Several miRNAs are being detected and related to metal exposure; however, there are still many differences in the expression profiles …
Mercury (Hg) is one of the most toxic metals in the environment, causing many adverse health effects. Its elimination is done by slowly conjunction with glutathione (GSH) through a detoxification system that involves several steps with this compound. Thus, the hypothesis being examined in this project is that the genetic polymorphism related to the enzyme-glutamyl-cysteine-ligase M (GCLM-…
| 1 / 1 | Ongoing research grants |
| 3 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 10 / 9 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 18 / 17 | All research grants and scholarships |
| Associated processes | |