Ana Carolina de Mattos Zeri

• Abstract

  The relationship between the three-dimensional structure of proteins and their functions is well-established, in which the arrangement of atoms determines the folding and, consequently, the shape and activity of the protein. Therefore, when analyzing the structure of these macromolecules, it is possible to identify mechanisms related to biological action and develop drugs that modulate th…

  Heterogeneous nucleation of protein crystals from the application of metal-organic frameworks, BP.IC

• Abstract

  In recent years, due to the growing global demand for energy, the dependence on fossil fuels and the limited natural ressources and environmental pollution, biofuels have attracted great interest as source of renewable energy. However, the production from plant biomass is still considered an expensive technology and with low efficiency. In this context, the study of carbohydrate binding …

  Study of the Molecular Basis of Carbohydrate Binding Modules (CBMs) from Metagenomic Screenings, BP.PD

• Abstract

  Bacterial cell division occurs through the formation of a contracting macromolecular complex, that yields two daughter cells. The key event is the assembly of a protein complex that changes the bacterial envelope growth direction, formed by a ring of FtsZ proteins, known as the Z ring, in the central region of the cell. Once the Z ring is formed, other proteins are recruited to the site, …

  Functional and structural characterization of the Bacillus's ZapA protein, BP.DR

(Only some records are available in English at this moment)

• Abstract

  In recent years, due to the growing global demand for energy, the dependence on fossil fuels, limited natural resources, and environmental pollution, biofuels have attracted great interest as source of renewable energy. However, production of biofuels from plant biomass is still considered an expensive technology with low efficiency. In this context, the study of carbohydrate binding mod…

  Study of the binding interactions of carbohydrate binding modules and carbohydrates, BE.EP.PD

• Abstract

  The applicant's mentor, Dr. Gerszten, and collaborators have identified and validated amino acid and lipid profiles of individuals destined to develop overt Diabetes Mellitus (DM) and atherosclerosis. In new unpublished work, the Gerszten laboratory has performed an analysis of "intermediate" metabolites using a recently-developed method for profiling organic acids, purines and pyrimidine…

  Metabolomic study of the biochemical mechanism of action of 2-aminoadipate in type 2 diabetes mellitus development, BE.EP.PD

• Abstract

  The bacterial division occurs through a citocinetic apparatus that shrinks, resulting in two daughter cells. This apparatus, also known as divisome, is a macromolecular complex responsible for the change in growth direction of the bacterial envelope (membrane and cell wall), creating the division septum. A key step in the division is the Z-ring formation, a prokaryotic tubulin polymer, Ft…

  Structural studies of the Bacillus stearothermophilus's ZapA protein, BE.EP.DR

(Only some records are available in English at this moment)