Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report

Full text
Author(s):
Dantas, Katia Cristina [1] ; de Freitas, Roseli Santos [2, 3] ; Pinto Garcia, Roberta Scholz [2, 3] ; da Silva, Marcos Vinicius [4] ; Mendes Muricy, Edna Cleide [2, 3] ; Kohara, Valdelene Sayuri [5] ; Vicentini, Adriana Pardini [5]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Sch Med, Dept Pathol, Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Trop Med, Sao Paulo - Brazil
[3] Univ Sao Paulo, Lab Med Mycol, LIM HCFMUSP 53, Sao Paulo - Brazil
[4] Emilio Ribas Infect Dis Inst, Sao Paulo - Brazil
[5] Adolfo Lutz Inst, Immunol Ctr, BR-01246902 Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Journal of Venomous Animals and Toxins including Tropical Diseases; v. 20, AUG 26 2014.
Web of Science Citations: 5
Abstract

This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases. (AU)