Latorre, Andreia O.
Greghi, Gisele F.
Netto, Arlindo Saran
Balieiro, Julio C.
Correa, Lisia B.
Zanetti, Marcus A.
Total Authors: 7
 Univ Sao Paulo, Dept Patol, Fac Med Vet & Zootecnia, BR-05508270 Sao Paulo - Brazil
 Fac Zootecnia & Engn Alimentos, Dept Zootecnia, BR-13630000 Pirassununga, SP - Brazil
 FZEA USP, Dept Zootecnia, Pirassununga, SP - Brazil
Total Affiliations: 3
Pesquisa Veterinária Brasileira;
Web of Science Citations:
A number of studies has shown that antioxidants, fatty acids and trace minerals may modulate different immune cell activities, and that their deficiency may be associated with diseases and impaired immune responses. In innate immunity, natural killer (NK) cells have a central role, killing virally infected and cancerous cells, and also secreting cytokines that shape adaptive immune responses. Thus, the aim of this study was to evaluate the effect of enriched diets in selenium plus vitamin E and/or canola oil on complete blood count and on NK cell cytotoxicity from blood lymphocytes of Nellore bulls. Bulls that received selenium plus vitamin E had (P=0.0091) higher NK cell cytotoxicity than control bulls. This result positively correlated with serum selenium levels. To the best of our knowledge, this is the first study that showed immunostimulatory effects of selenium plus vitamin E on NK cell cytotoxicity of Nellore bulls. (AU)