Determination of tetrakis(hydroxymethyl)phosphonium sulfate in commercial formulations and cooling water by capillary electrophoresis with contactless conductivity detection

Author(s)

Marques, Thais Tamye ^[1] ; Shiroma, Leticia Sayuri ^[1] ; de Jesus, Dosil Pereira ^{[1, 2]}

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil

^[2] Inst Nacl Ciencia & Tecnol Bioanalit, Campinas, SP - Brazil

• Document type: Journal article
• Source: JOURNAL OF SEPARATION SCIENCE; v. 38, n. 5, p. 852-857, MAR 2015.
• Web of Science Citations: 6

Abstract

A novel capillary electrophoresis method using capacitively coupled contactless conductivity detection is proposed for the determination of the biocide tetrakis(hydroxymethyl)phosphonium sulfate. The feasibility of the electrophoretic separation of this biocide was attributed to the formation of an anionic complex between the biocide and borate ions in the background electrolyte. Evidence of this complex formation was provided by B-11 NMRspectroscopy. A linear relationship (R-2 = 0.9990) between the peak area of the complex and the biocide concentration (50-900 mu mol/L) was found. The limit of detection and limit of quantification were 15.0 and 50.1 mu mol/L, respectively. The proposed method was applied to the determination of tetrakis(hydroxymethyl)phosphonium sulfate in commercial formulations, and the results were in good agreement with those obtained by the standard iodometric titrationmethod. Themethod was also evaluated for the analysis of tap water and cooling water samples treated with the biocide. The results of the recovery tests at three concentration levels (300, 400, and 600 mu mol/L) varied from 75 to 99%, with a relative standard deviation no higher than 9%. (AU)

• FAPESP's process: 13/22485-6 - Development and application of electromembrane extraction in capillary electrophoresis methods
• Grantee: Dosil Pereira de Jesus
• Support Opportunities: Regular Research Grants