The combined effect of physical activity and sedentary behaviors on a clustered cardio-metabolic risk score: The Helena study

Author(s):Show less -

Rendo-Urteaga, Tara ^{[1, 2]} ; Cesar Ferreira de Moraes, Augusto ^{[1, 2]} ; Sadalla Collese, Tatiana ^{[1, 2]} ; Manios, Yannis ^[3] ; Hagstromer, Maria ^[4] ; Sjostrom, Michael ^[5] ; Kafatos, Anthony ^[6] ; Widhalm, Kurt ^[7] ; Vanhelst, Jeremy ^{[8, 9]} ; Marcos, Ascension ^[10] ; Gonzalez-Gross, Marcela ^{[11, 12]} ; De Henauw, Stefaan ^{[13, 14]} ; Ciarapica, Donatella ^[15] ; Ruiz, Jonatan R. ^{[5, 16]} ; Espana-Romero, Vanesa ^[17] ; Molnar, Denes ^[18] ; Carvalho, Heraclito B. ^[1] ; Moreno, Luis A. ^{[2, 19]} ; Grp, HELENA Study

Affiliation:Show less -

^[1] Univ Sao Paulo, Sch Med, Res Grp, Youth Child & cARdiovasc Risk & Environm YCARE, Sao Paulo, SP - Brazil

^[2] Univ Zaragoza, Sch Hlth Sci EUCS, Res Grp, Growth Exercise NUtr & Dev GENUD, Zaragoza - Spain

^[3] Harokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens - Greece

^[4] Karolinska Inst, Div Physiotherapy, Dept Neurobiol Care Sci & Soc, Huddinge - Sweden

^[5] Karolinska Inst, Dept Biosci & Nutr, Unit Prevent Nutr, Huddinge - Sweden

^[6] Univ Crete, Prevent Med & Nutr Clin, Sch Med, Dept Social Med, Iraklion - Greece

^[7] Private Med Univ, Dept Pediat, Salzburg - Austria

^[8] Univ Lille Nord France, INSERM, U995, Lille - France

^[9] Univ Hosp, INSERM, CH&U, CIC PT 1403, Lille - France

^[10] CSIC, Inst Frio, Inst Food Sci & Technol Nutr ICTAN, Inmunonutr Res Grp, Dept Metab & Nutr, Spanish Natl, E-28040 Madrid - Spain

^[11] Tech Univ Madrid, Fac Phys Act & Sport INEF, Dept Hlth & Human Performance, ImFINE Res Grp, Madrid - Spain

^[12] Univ Bonn, Inst Ernahrungs & Lebensmittelwissensch Ernahrung, Bonn - Germany

^[13] Univ Ghent, Dept Publ Hlth, B-9000 Ghent - Belgium

^[14] Univ Coll Ghent Vesalius, Ghent - Belgium

^[15] Res Ctr Food & Nutr CRA NUT, Agr Res Council, Rome - Italy

^[16] Univ Granada, Fac Sport Sci, Dept Phys Educ & Sports, PROFITH PROmoting FITness & Hlth Phys Act Res Grp, Granada - Spain

^[17] Univ Cadiz, Sch Educ, Dept Phys Educ, Cadiz - Spain

^[18] Univ Pecs, Fac Med, Dept Pediat, Pecs - Hungary

^[19] Univ Sao Paulo, Sch Med, Dept Prevent Med, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF CARDIOLOGY; v. 186, p. 186-195, MAY 1 2015.
• Web of Science Citations: 31

Abstract

Background/objective: Increased physical activity (PA) and decreased sedentary behaviors (SBs) may have beneficial effects on cardio-metabolic risk in adolescents. The aim of this study was to examine the associations between independent/combined effects of PA and SB with individual/clustered cardio-metabolic risk factors. Methods: A sample of 769 adolescents (12.5-17.5 years) from the HELENA cross-sectional study (Healthy Lifestyle in Europe by Nutrition in Adolescence) and with valid data on metabolic risk factors were included. Results: Concerning moderate-to-vigorous-PA (MVPA) and vigorous-PA (VPA), measured with accelerometers, girls tended to domoreMVPA (36%) and VPA (114%) than boys. Unadjusted analyses show a positive association between ``PA >= 60 min/d; SB >= 2 h{''} and the ratio TC/HDL-c (beta = 0.27; 95% CI 0.01 to 0.52; p < 0.05), and a negative association between ``MVPA = 60 min/d; SB < 2 h{''} with the Sigma 4Skinfolds (beta = -0.32; 95% CI - 0.61 to -0.02; p < 0.05). Moreover, ``SB >= 2 h/d{''} was associated with increased cardio-metabolic risk (PR 1.59; 95% CI 1.05 to 2.39; p < 0.05), while ``PA >= 60 min/d; SB < 2 h{''} had a protective effect against cardio-metabolic risk (PR 0.48; 95% CI 0.25 to 0.91; p < 0.05). After adjustment for potential confounders, a positive association between SB and Sigma 4Skinfolds was shown (beta = 0.28; 95% CI 0.04 to 0.53; p < 0.05). Furthermore, VO(2)max (mL/kg/min) tends to increase in those participants who do higher VPA and less SB (p = 0.042), and there was a protective effect of ``VPA >= 30 min/d; SB < 2 h{''} against cardio-metabolic risk (PR 0.24; 95% CI 0.07 to 0.85; p < 0.05). Conclusion: The current study suggests that adolescents should be encouraged to decrease sedentary lifestyle and increase physical activity, especially vigorous physical activity, in order to reduce cardio-metabolic risk. (C) 2015 Elsevier Ireland Ltd. All rights reserved. (AU)

• FAPESP's process: 11/11137-1 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study
• Grantee: Augusto César Ferreira de Moraes
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 11/20662-2 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study
• Grantee: Augusto César Ferreira de Moraes
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate