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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Antimicrobial resistance and virulence gene profiles in P. multocida strains isolated from cats

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Porfida Ferreira, Thais Sebastiana [1] ; Felizardo, Maria Roberta [1] ; Sena de Gobbi, Debora Dirani [1] ; Moreno, Marina [1] ; Moreno, Andrea Micke [1]
Total Authors: 5
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Lab Epidemiol Mol & Resistencia Antimicrobianos, BR-05508270 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Brazilian Journal of Microbiology; v. 46, n. 1, p. 271-277, MAY 2015.
Web of Science Citations: 2

Cats are often described as carriers of Pasteurella multocida in their oral microbiota. This agent is thought to cause pneumonia, conjunctivitis, rhinitis, gingivostomatitis, abscess and osteonecrosis in cats. Human infection with P. multocida has been described in several cases affecting cat owners or after cat bites. In Brazil, the cat population is approximately 21 million animals and is increasing, but there are no studies of the presence of P. multocida in the feline population or of human cases of infection associated with cats. In this study, one hundred and ninety-one healthy cats from owners and shelters in Sao Paulo State, Brazil, were evaluated for the presence of P. multocida in their oral cavities. Twenty animals were positive for P. multocida, and forty-one strains were selected and characterized by means of biochemical tests and PCR. The P. multocida strains were tested for capsular type, virulence genes and resistance profile. A total of 75.6% (31/41) of isolates belonged to capsular type A, and 24.4% (10/41) of the isolates were untypeable. None of the strains harboured toxA, tbpA or pfhA genes. The frequencies of the other genes tested were variable, and the data generated were used to build a dendrogram showing the relatedness of strains, which were clustered according to origin. The most common resistance profile observed was against sulfizoxazole and trimethoprim-sulphamethoxazole. (AU)

FAPESP's process: 07/08592-3 - Isolation and characterization of p. multocida from cats and dogs
Grantee:Thaís Sebastiana Porfida Ferreira
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 07/03024-7 - Evaluation of serological and contamination profile of Pasteurella multocida in swine herds
Grantee:Andrea Micke Moreno
Support type: Regular Research Grants