Non-Invasive Salivary Electrochemical Quantification of Paraquat Poisoning Using Boron Doped Diamond Electrode

Author(s)

Guimaraes Selva, Thiago Matheus ^{[1, 2]} ; de Araujo, William Reis ^[1] ; Longo Cesar da Paixao, Thiago Regis ^[1]

Affiliation

^[1] Univ Sao Paulo, Inst Quim, BR-05508000 Sao Paulo, SP - Brazil

^[2] Inst Fed Educ Ciencia & Tecnol Pernambuco, BR-50740540 Recife, PE - Brazil

• Document type: Journal article
• Source: Electroanalysis; v. 27, n. 7, p. 1642-1648, JUL 2015.
• Web of Science Citations: 7

Abstract

The present work describes the first electrochemical method for quantifying paraquat herbicide poisoning in human saliva samples. Paraquat shows two couples of well-defined peaks in aqueous solution using a boron doped diamond (BDD) electrode. By using square wave voltammetry (SWV) technique under optimum experimental conditions, a linear analytical curve was obtained for paraquat concentrations ranging from 0.800 to 167 mu molL(-1), with a detection limit of 70 nmolL(-1). This method was applied to quantify paraquat spikes in human saliva samples and in two different water samples (tap and river). The recovery values obtained ranged from 83.0 to 104% and 99.1 to 105%, respectively, which highlight the accuracy of the proposed method. (AU)

• FAPESP's process: 12/12106-5 - Development of intelligent devices (electronic noses and tongues) using electrochemical, colorimetric and mass measurements aiming to the discrimination of forensic and food samples
• Grantee: Thiago Regis Longo Cesar da Paixão
• Support Opportunities: Regular Research Grants
• FAPESP's process: 11/19903-5 - Development of electroanalytical methods for detection/discrimination of drugs of abuse, its adulterants and explosives in forensic samples
• Grantee: William Reis de Araujo
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)