| Full text | |
| Author(s): |
Total Authors: 4
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| Affiliation: | [1] Univ Sao Paulo, Inst Chem Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | JOURNAL OF SEPARATION SCIENCE; v. 38, n. 17, p. 3071-3083, SEP 2015. |
| Web of Science Citations: | 5 |
| Abstract | |
The concept of unified chromatography has been in existence for 50 years after the work of Giddings proposing that all modes of chromatography (gas chromatography, liquid chromatography, supercritical fluid chromatography and so on) may be treated together under a single unified theory. His idea was partially fulfilled 23 years later by Ishii, Takeuchi and colleagues, who demonstrated for the first time the possibility to analyze a complex sample containing substances with a wide range of boiling points and polarities in the same instrument and column, just by varying the mobile phase pressure and temperature to change from one chromatographic mode to another. This approach has been demonstrated through application to the separation of complex mixtures in several areas including crude oil, edible oils and polymers. Still, unified chromatography has not yet been fully developed. In the present work, we will review the fundamentals, instrumentation and several applications of the technique. Also discussed are the drawbacks that still hinder development, as well as the recent developments and trends in instrumentation and columns that suggest the most feasible ways forward to the full development of unified chromatography. (AU) | |
| FAPESP's process: | 11/09898-4 - Development of molecularly imprinted polymer and use for the sample preparation and analysis of triazine and sulfonylurea in maize using high performance liquid chromatography (HPLC). |
| Grantee: | Felipe Nascimento Andrade |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 12/22055-9 - Development of silica modified with ionic liquids and their use in sample preparation techniques |
| Grantee: | Meire Ribeiro da Silva |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 14/07347-9 - Development of novel materials and devices for miniaturized sample preparation techniques in the area of food safety |
| Grantee: | Fernando Mauro Lanças |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/17425-4 - Evaluation of MEPS technique applied in pesticides analysis in sugarcane juice by GC-MS |
| Grantee: | Bruno Henrique Fumes |
| Support Opportunities: | Scholarships in Brazil - Master |