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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Physical Activity Modifies the Associations between Genetic Variants and Blood Pressure in European Adolescents

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Author(s):
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Ferreira de Moraes, Augusto Cesar [1, 2, 3] ; Miguel Fernandez-Alvira, Juan [2, 3] ; Carvalho, Heraclito Barbosa [1] ; Meirhaeghe, Aline [4, 5] ; Dallongeville, Jean [4, 5] ; Kafatos, Anthony [6] ; Marcos, Ascension [7] ; Molnar, Denes [8] ; Manios, Yannis [9] ; Ruiz, Jonatan R. [10] ; Labayen, Idoia [11] ; Widhalm, Kurt [12] ; Breidenassel, Christina [13] ; Gonzalez-Gross, Marcela [13, 14] ; Moreno, Luis A. [3, 2]
Total Authors: 15
Affiliation:
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[1] Univ Sao Paulo, Sch Med, Dept Prevent Med, Sao Paulo - Brazil
[2] Univ Zaragoza, Fac Hlth Sci, Zaragoza - Spain
[3] Univ Zaragoza, GENUD Growth Exercise Nutr & Dev Res Grp, Zaragoza - Spain
[4] Univ Lille Nord France, Inst Pasteur Lille, INSERM, U744, Lille - France
[5] UDSL, Lille - France
[6] Univ Crete, Prevent Med & Nutr Unit, Sch Med, Iraklion, Crete - Greece
[7] Spanish Natl Res Council, Dept Metab & Nutr, Food Sci & Technol & Nutr Inst, Immunonutr Res Grp, Madrid - Spain
[8] Univ Pecs, Fac Med, Dept Pediat, Pecs - Hungary
[9] Harokopio Univ, Dept Nutr & Dietet, Athens - Greece
[10] Univ Granada, Fac Sport Food Sci, Dept Phys Educ & Sports, Promoting Fitness & Hlth Phys Act Res Grp, Granada - Spain
[11] Univ Basque Country, Dept Nutr & Food Sci, Vitoria - Spain
[12] Private Med Univ Salzburg, Dept Pediat, Salzburg - Austria
[13] Univ Bonn, Inst Ernahrungs & Lebensmittelwissensch Humanerna, Bonn - Germany
[14] Tech Univ Madrid, Fac Phys Act & Sport INEF, Dept Hlth & Human Performance, Madrid - Spain
Total Affiliations: 14
Document type: Journal article
Source: JOURNAL OF PEDIATRICS; v. 165, n. 5, p. 1046-U237, NOV 2014.
Web of Science Citations: 3
Abstract

We hypothesized that physical activity and sedentary behavior could modify the associations between known genetic variants blood pressure-associated genes in European adolescents. Meeting current physical activity recommendations (>= 60 minutes/day) was able attenuate the deleterious effect of the NOS3 rs3918227 polymorphism on systolic blood pressure in European adolescents. (AU)

FAPESP's process: 11/11137-1 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study
Grantee:Augusto César Ferreira de Moraes
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 11/20662-2 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study
Grantee:Augusto César Ferreira de Moraes
Support type: Scholarships abroad - Research Internship - Doctorate