Purple carrots: Better biocatalysts for the enantioselective reduction of acetophenones than common orange carrots (D. carota)

Author(s)

Omori, Alvaro Takeo ^[1] ; Lobo, Flavia Goncalves ^[1] ; Goncalves do Amaral, Anna Carolina ^[1] ; de Oliveira, Camila de Souza ^[1]

Affiliation

^[1] Univ Fed ABC, Ctr Ciencias Nat & Humanas, Lab Compostos Bioat, R Santa Adelia 166, BR-09210170 Santo Andre - Brazil

• Document type: Journal article
• Source: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC; v. 127, p. 93-97, MAY 2016.
• Web of Science Citations: 7

Abstract

The constant and reproducible enantioselective reduction of acetophenones were investigated in several edible plants. Among them, only carrot (Daucus carota) acted as a reliable biocatalyst. Different carrot varieties (orange, yellow and purple carrots) in contact with substituted acetophenones gave the corresponding optically-active alcohols in good-to-excellent rates of conversion with high enantioselectivity. Comparatively, the purple carrot was a better biocatalyst than the common orange variety. (C) 2016 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 09/00617-2 - Biocatalysis: the use of plant cells and lipases in organic synthesis - application on asymmetric synthesis of biologically active compounds
• Grantee: Alvaro Takeo Omori
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 14/25659-8 - Studies aiming the asymmetric total synthesis of caramboxin
• Grantee: Alvaro Takeo Omori
• Support Opportunities: Regular Research Grants