First Characterization of CTX-M-15-Producing Escherichia coli Strains Belonging to Sequence Type (ST) 410, ST224, and ST1284 from Commercial Swine in South America

Author(s)

Silva, Ketrin C. ^[1] ; Moreno, Marina ^[1] ; Cabrera, Carlos ^[1] ; Spira, Beny ^[2] ; Cerdeira, Louise ^{[2, 3]} ; Lincopan, Nilton ^{[2, 3]} ; Moreno, Andrea M. ^[1]

Affiliation

^[1] Univ Sao Paulo, Sch Vet Med, Dept Prevent Med & Anim Hlth, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil

^[3] Univ Sao Paulo, Sch Pharm, Dept Clin Anal, Sao Paulo - Brazil

• Document type: Journal article
• Source: Antimicrobial Agents and Chemotherapy; v. 60, n. 4, p. 2505-2508, APR 2016.
• Web of Science Citations: 8

Abstract

We report for the first time the isolation of CTX-M-15-producing Escherichia coli strains belonging to sequence type (ST) 410, ST224, and ST1284 in commercial swine in Brazil. The bla(CTX-M-15) gene was located on F-::A9::B1 and C1::A9::B1 IncF-type plasmids, surrounded by a new genetic context comprising the IS26 insertion sequence truncated with the ISEcp1 element upstream of bla(CTX-M-15). These results reveal that commercial swine have become a new reservoir of CTX-M-15-producing bacteria in South America. (AU)

• FAPESP's process: 12/08332-0 - Molecular characterization of plasmids harboring extended-spectrum Beta-lactamase-encoding genes in Enterobacteriaceas isolated from swine
• Grantee: Ketrin Cristina da Silva
• Support Opportunities: Scholarships in Brazil - Doctorate