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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Genome-Wide Association Study of Meat Quality Traits in Nellore Cattle

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Magalhaes, Ana F. B. [1] ; de Camargo, Gregorio M. F. [1, 2] ; Fernandes Junior, Gerardo A. [1] ; Gordo, Daniel G. M. [1] ; Tonussi, Rafael L. [1] ; Costa, Raphael B. [1, 3] ; Espigolan, Rafael [1] ; Silva, Rafael M. de O. [1] ; Bresolin, Tiago [1] ; de Andrade, Willian B. F. [1] ; Takada, Luciana [1] ; Feitosa, Fabieli L. B. [1] ; Baldi, Fernando [1] ; Carvalheiro, Roberto [4, 1] ; Chardulo, Luis A. L. [4, 5] ; de Albuquerque, Lucia G. [1, 4]
Total Authors: 16
[1] Fac Ciencias Agr & Vet, Dept Zootecnia, Jaboticabal, SP - Brazil
[2] Univ Tecnol Parana, Dois Vizinhos, Parana - Brazil
[3] Univ Fed Bahia, Dept Med Vet Prevent & Prod Anim, Salvador, BA - Brazil
[4] Conselho Nacl Desenvolvimento Cient & Tecnol CNPq, Brasilia, DF - Brazil
[5] Fac Med Vet & Zootecnia, Dept Melhoramento & Nutr Anim, Botucatu, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: PLoS One; v. 11, n. 6 JUN 30 2016.
Web of Science Citations: 22

The objective of this study was to identify genomic regions that are associated with meat quality traits in the Nellore breed. Nellore steers were finished in feedlots and slaughtered at a commercial slaughterhouse. This analysis included 1,822 phenotypic records of tenderness and 1,873 marbling records. After quality control, 1,630 animals genotyped for tenderness, 1,633 animals genotyped for marbling, and 369,722 SNPs remained. The results are reported as the proportion of variance explained by windows of 150 adjacent SNPs. Only windows with largest effects were considered. The genomic regions were located on chromosomes 5, 15, 16 and 25 for marbling and on chromosomes 5, 7, 10, 14 and 21 for tenderness. These windows explained 3,89% and 3,80% of the additive genetic variance for marbling and tenderness, respectively. The genes associated with the traits are related to growth, muscle development and lipid metabolism. The study of these genes in Nellore cattle is the first step in the identification of causal mutations that will contribute to the genetic evaluation of the breed. (AU)

FAPESP's process: 09/16118-5 - Genomic tools to genetic improvement of direct economic important traits in Nelore cattle
Grantee:Lucia Galvão de Albuquerque
Support type: Research Projects - Thematic Grants
FAPESP's process: 12/21969-7 - Use of genomic information for genetic improvement of traits in beef cattle Nellore
Grantee:Ana Fabrícia Braga Magalhães
Support type: Scholarships in Brazil - Doctorate