Pre-Exercise Infrared Low-Level Laser Therapy (810nm) in Skeletal Muscle Performance and Postexercise Recovery in Humans, What Is the Optimal Dose? A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Author(s)

Vanin, Adriane Aver ; De Marchi, Thiago ; Tomazoni, Shaiane Silva ; Tairova, Olga ; Casalechi, Heliodora Leao ; Camillo de Carvalho, Paulo de Tarso ; Bjordal, Jan Magnus ; Leal-Junior, Ernesto Cesar

• Document type: Journal article
• Source: Photomedicine and Laser Surgery; v. 34, n. 10, p. 473-482, OCT 2016.
• Web of Science Citations: 17

Abstract

Aim: This study aimed to evaluate the medium-term effects of low-level laser therapy (LLLT or photobiomodulation) in postexercise skeletal muscle recovery and performance enhancement and to identify the optimal dose of 810nm LLLT. Materials and methods: A randomized, double-blind, placebo-controlled trial was performed, with voluntary participation of 28 high-level soccer athletes. We analyzed maximum voluntary contraction (MVC), delayed onset muscle soreness (DOMS), creatine kinase (CK) activity, and interleukin-6 (IL-6) expression. The assessments were performed before exercise protocols, after 1min, and 1, 24, 48, 72, and 96h after the end of eccentric exercise protocol used to induce fatigue. LLLT was applied before eccentric exercise protocol with a cluster with five diodes, and dose of 10, 30, or 50J (200mW and 810nm) in six sites of quadriceps. Results: LLLT increased (p<0.05) MVC from immediately after exercise to 24h with 50J dose, and from 24 to 96h with 10J dose. Both 10J then 50J dose decreased (p<0.05) CK and IL-6 with better results in favor of 50J dose. However, LLLT had no effect in decreasing DOMS. No differences (p>0.05) were found for 30J dose in any of the outcomes measured. Conclusions: Pre-exercise LLLT, mainly with 50J dose, significantly increases performance and improves biochemical markers related to skeletal muscle damage and inflammation. (AU)

• FAPESP's process: 12/02442-8 - Low-level laser therapy in skeletal muscle fatigue and post-exercise recovery: What is the ideal dose?
• Grantee: Adriane Aver Vanin
• Support type: Scholarships in Brazil - Master
• FAPESP's process: 10/52404-0 - Low-level laser therapy in skeletal muscle fatigue and post-exercise recovery: Optimal parameters and effects in long-duration exercise
• Grantee: Ernesto Cesar Pinto Leal Junior
• Support type: Research Grants - Young Investigators Grants
• FAPESP's process: 13/19355-3 - Phototherapy associated to muscular training: Evaluation of different protocols of irradiation
• Grantee: Adriane Aver Vanin
• Support type: Scholarships in Brazil - Doctorate