Employment of graphene as sorbent in miniaturized sample preparation techniques
| Full text | |
| Author(s): |
Fumes, Bruno Henrique
;
Lancas, Fernando Mauro
Total Authors: 2
|
| Document type: | Journal article |
| Source: | Journal of Chromatography A; v. 1487, p. 64-71, MAR 3 2017. |
| Web of Science Citations: | 16 |
| Abstract | |
This paper describes the synthesis, characterization and use of graphene supported on aminopropyl silica through covalent bonds (Si-G) as a sorbent for microextraction by packed sorbent (MEPS). Five parabens (methyl, ethyl, propyl, butyl and benzyl) present in water matrices were used as model compounds for this evaluation. The Si-G phase was compared to other sorbents used in MEPS (C18 and Strata(Tm)-X) and also with graphene supported on primary-secondary amine (PSA) silica, where Si-G showed better results. After this, the MEPS experimental parameters were optimized using the Si-G sorbent. The following variables were optimized through univariate experiments: pH (4,7 and 10), desorption solvent (ACN:MeOH (50:50), ACN:H2O (40:60), MeOH and ACN) and ionic strength (0, 10 and 20% of NaCI). A factorial design 2(6-2) was then employed to evaluate other variables, such as the sample volume, desorption volume, sampling cycles, wash cycles and desorption cycles, as well as the influence of NaCI% on the extraction performance. The optimized method achieved a linear range of 0.2-20 mu g/L for most parabens; weighted calibration models were employed during the linearity evaluation to reduce the absolute sum of the residue values and improve R-2, which ranged from 0.9753 to 0.9849. The method's accuracy was 82.3-119.2%; precision, evaluated as the coefficient of variance for intraday and interday analysis, ranged from 1.5 to 19.2%. After evaluation of the figures of merit, the method was applied to the determination of parabens in water samples. (C) 2017 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 15/15462-5 - Employment of graphene as sorbent in miniaturized sample preparation techniques |
| Grantee: | Bruno Henrique Fumes |
| Support type: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 14/07347-9 - Development of novel materials and devices for miniaturized sample preparation techniques in the area of food safety |
| Grantee: | Fernando Mauro Lanças |
| Support type: | Regular Research Grants |