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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pediococcus spp.: An important genus of lactic acid bacteria and pediocin producers

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Porto, Maria Carolina W. ; Kuniyoshi, Tais Mayumi ; Azevedo, P. O. S. ; Vitolo, Michele ; Oliveira, R. P. S.
Total Authors: 5
Document type: Review article
Source: BIOTECHNOLOGY ADVANCES; v. 35, n. 3, p. 361-374, MAY-JUN 2017.
Web of Science Citations: 28

Probiotics have gained increasing attention due to several health benefits related to the human digestive and immune systems. Pediococcus spp. are lactic acid bacteria (LAB) that are widely described as probiotics and characterized as coccus-shaped bacteria (arranged in tetrads), Gram-positive, non-motile, non-spore forming, catalase-negative, and facultative anaerobes. There are many Pediococcus strains that produce pediocin, an effective antilisterial bacteriocin. Pediocins are small, cationic molecules consisting of a conserved hydrophilic N-terminal portion containing the YGNGV motif and an amphiphilic or hydrophobic C-terminal variable portion. A number of studies have been developed with Pediococcus isolated from multiple biological niches to conduct fermentation processes for pediocin or Pediococcus cell production. This review gathers the most significant information about the cultivation, mode of action, and variability of bacteriocins produced by Pediococcus spp., emphasizing their applications in the areas of food and clinical practice. This updated panorama assists in delimiting the challenges that still need to be overcome for pediocin use to be approved for human consumption and the food industry. (C) 2017 Elsevier Inc. All rights reserved. (AU)

FAPESP's process: 16/06284-9 - Biotechnology production of pediocin: optimization of yield and biological effects on cells of the immune system
Grantee:Ricardo Pinheiro de Souza Oliveira
Support type: Regular Research Grants
FAPESP's process: 15/24777-0 - Optimization of pediocin a production in Pediococcus pentosaceus ATCC 43200
Grantee:Taís Mayumi Kuniyoshi
Support type: Scholarships in Brazil - Post-Doctorate