| Full text | |
| Author(s): |
Lima, Rafaely N.
;
Porto, Andre L. M.
Total Authors: 2
|
| Document type: | Journal article |
| Source: | Catalysis Communications; v. 100, p. 157-163, SEP 2017. |
| Web of Science Citations: | 5 |
| Abstract | |
Enzymes play many roles in the advancement of biotechnology, discovery of new therapeutic agents and industrial processes. In this perspective, aminolysis reactions using lipase from Candida antarctica (CAL-B) were performed from ethyl (S)-mandelate and several aliphatic amines (45 degrees C, hexane, 3-6 h). By means of optimized conditions, amides with excellent isolated yields (60-97%) were synthetized. The biotechnological potential of CAL-B as a promising approach for the synthesis of organic compounds in a more sustainable, rapid, efficient and green chemistry perspective was verified on these results. (AU) | |
| FAPESP's process: | 14/18257-0 - New approaches in biocatalytic reactions |
| Grantee: | Andre Luiz Meleiro Porto |
| Support type: | Regular Research Grants |