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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Biocatalytic aminolysis of ethyl (S)-mandelate by lipase from Candida antarctica

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Author(s):
Lima, Rafaely N. ; Porto, Andre L. M.
Total Authors: 2
Document type: Journal article
Source: Catalysis Communications; v. 100, p. 157-163, SEP 2017.
Web of Science Citations: 5
Abstract

Enzymes play many roles in the advancement of biotechnology, discovery of new therapeutic agents and industrial processes. In this perspective, aminolysis reactions using lipase from Candida antarctica (CAL-B) were performed from ethyl (S)-mandelate and several aliphatic amines (45 degrees C, hexane, 3-6 h). By means of optimized conditions, amides with excellent isolated yields (60-97%) were synthetized. The biotechnological potential of CAL-B as a promising approach for the synthesis of organic compounds in a more sustainable, rapid, efficient and green chemistry perspective was verified on these results. (AU)

FAPESP's process: 14/18257-0 - New approaches in biocatalytic reactions
Grantee:Andre Luiz Meleiro Porto
Support type: Regular Research Grants