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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration

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Author(s):
Deschk, Mauricio [1] ; Trein, Thomas Alexander [2] ; Wagatsuma, Juliana Tessalia [2] ; da Silva, Guilherme Lopes [2] ; de Araujo, Marcelo Augusto [3] ; Martins Games, Bruna de Moraes [2] ; Alcindo, Jefferson Filgueira [2] ; Rodrigues, Celso Antonio [1] ; Patto dos Santos, Paulo Sergio [2]
Total Authors: 9
Affiliation:
[1] Univ Estadual Paulista, UNESP, Fac Med Vet & Zootecnia, Botucatu, SP - Brazil
[2] Univ Estadual Paulista, UNESP, Fac Med Vet, Aracatuba, SP - Brazil
[3] Univ Fed Mato Grosso do Sul UFMS, Fac Med Vet & Zootecnia, Campo Grande, MS - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Ciência Rural; v. 47, n. 11 2017.
Web of Science Citations: 0
Abstract

ABSTRACT: The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time. (AU)

FAPESP's process: 13/09469-1 - BISPECTRAL INDEX, HEMODYNAMIC AND RESPIRATORY EFFECTS OF CONTINUOUS INFUSION PROPOFOL ASSOCIATED OR NOT TO FENTANYL IN CALVES
Grantee:Mauricio Deschk
Support Opportunities: Scholarships in Brazil - Doctorate