Effects of supplementation with L-glutamine and L-alanine in the body composition of rats submitted to resistance exercise

Author(s)

Audrey Yule Coqueiro ^[1] ; Raquel Raizel ^[2] ; Thaís Menezes Hypólito ^[3] ; Julio Tirapegui ^[4]

Affiliation

^[1] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Alimentos e Nutrição Experimental - Brasil

^[2] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Alimentos e Nutrição Experimental - Brasil

^[3] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Alimentos e Nutrição Experimental - Brasil

^[4] Universidade de São Paulo. Faculdade de Ciências Farmacêuticas. Departamento de Alimentos e Nutrição Experimental - Brasil

• Document type: Journal article
• Source: Rev. Bras. Ciênc. Esporte; v. 39, n. 4, p. 417-423, 2017-12-00.

Abstract

Abstract We investigated the effects of glutamine and alanine supplementation on body composition of rats submitted to resistance exercise. Wistar rats were submitted to eight-week of resistance exercise, which consisted of climbing a ladder with progressive loads (25–100% of body weight). In the last 21 days of training, animals were supplemented with L-glutamine and L-alanine, as a dipeptide or in their free form (DIP, GLN + ALA and ALA groups), or water (SED and CTRL groups). RE attenuated body weight gain and lipid contents of CTRL group (p < 0.05 vs. SED) and DIP supplementation promoted an increase in tibialis muscle weight, as well as in protein content (p < 0.05 vs. CTRL). Taken together, our data indicated that resistance exercise improves body composition and dipeptide potentiated the muscle hypertrophic effect. (AU)

• FAPESP's process: 12/21087-4 - Effect of nutritional intervention and resistance training in ovariectomized rats and/or in rats subjected to an intense workout protocol
• Grantee: Julio Orlando Tirapegui Toledo
• Support Opportunities: Regular Research Grants