| Full text | |
| Author(s): |
Piccoli, Julia
[1]
;
Hein, Robert
[2]
;
El-Sagheer, Afaf H.
[2, 3]
;
Brown, Tom
[2]
;
Cilli, Eduardo M.
[1]
;
Bueno, Paulo R.
[1]
;
Davis, Jason J.
[2]
Total Authors: 7
|
| Affiliation: | [1] Sao Paulo State Univ UNESP, Inst Chem, BR-14800900 Araraquara, SP - Brazil
[2] Univ Oxford, Dept Chem, South Parks Rd, Oxford OX1 3QZ - England
[3] Suez Univ, Fac Petr & Min Engn, Chem Branch, Dept Sci & Math, Suez 43721 - Egypt
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Analytical Chemistry; v. 90, n. 5, p. 3005-3008, MAR 6 2018. |
| Web of Science Citations: | 13 |
| Abstract | |
Electrochemical immunosensors offer much in the potential translation of a lab based sensing capability to a useful ``real world{''} platform. In previous work we have introduced an impedance-derived electrochemical capacitance spectroscopic analysis as supportive of a reagentless means of reporting on analyte target capture at suitably prepared mixed-component redox-active, antibody-modified interfaces. Herein we directly integrate receptive aptamers into a redox charging peptide support in enabling a label-free low picomolar analytical assay for C-reactive protein with a sensitivity that significantly exceeds that attainable with an analogous antibody interface. (AU) | |
| FAPESP's process: | 15/02343-8 - Controlled release of peptides from latex biomembranes and development of capacitive biosensors containing self-assembled peptide |
| Grantee: | Eduardo Maffud Cilli |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery |
| Grantee: | Glaucius Oliva |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |
| FAPESP's process: | 12/22820-7 - The sensitive label free detection of disease markers using electrochemical immittance |
| Grantee: | Eduardo Maffud Cilli |
| Support Opportunities: | Research Projects - Thematic Grants |