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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Data-Driven Corpus Callosum Parcellation Method Through Diffusion Tensor Imaging

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Author(s):
Cover, Giovana [1] ; Pereira, Mariana [1] ; Bento, Mariana [2] ; Appenzeller, Simone [1] ; Rittner, Leticia [3]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Sch Elect & Comp Engn, Med Image Comp Lab, BR-13083852 Campinas, SP - Brazil
[2] Univ Calgary, Hotchkiss Brain Inst, Radiol & Clin Neurosci, BR-13083852 Calgary, AB T2N 1N4 - Canada
[3] Univ Estadual Campinas, Fac Med Sci, Rheumatol Dept, BR-13083970 Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: IEEE ACCESS; v. 5, p. 22421-22432, 2017.
Web of Science Citations: 1
Abstract

The corpus callosum (CC) is a set of neural fibers in the cerebral cortex, responsible for facilitating inter-hemispheric communication. The CC structural characteristics appear as an essential element for studying healthy subjects and patients diagnosed with neurodegenerative diseases. Due to its size, the CC is usually divided into smaller regions, also known as parcellation. Since there are no visible landmarks inside the structure indicating its division, CC parcellation is a challenging task and methods proposed in the literature are geometric or atlas-based. This paper proposed an automatic data-driven CC parcellation method, based on diffusion data extracted from diffusion tensor imaging that uses the Watershed transform. Experiments compared parcellation results of the proposed method with results of three other parcellation methods on a data set containing 150 images. Quantitative comparison using the Dice coefficient showed that the CC parcels given by the proposed method has a mean overlap higher than 0,9 for some parcels and lower than 0,6 for other parcels. Poor overlap results were confirmed by the statistically significant differences obtained for diffusion metrics values in each parcel, when using different parcellation methods. The proposed method was also validated by using the CC tractography and was the only study that proposed a non-geometric approach for the CC parcellation, based only on the diffusion data of each subject analyzed. (AU)

FAPESP's process: 13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology
Grantee:Fernando Cendes
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC