Cardiovascular Adaptations Induced by Resistance Training in Animal Models

Author(s)

Melo, S. F. S. ^[1] ; Silva Junior, N. D. ^[2] ; Barauna, V. G. ^[1] ; Oliveira, E. M. ^[2]

Affiliation

^[1] Univ Fed Espirito Santo, Hlth Sci Ctr, Lab Mol Physiol, Av Marechal Campos, 1468 Maruipe, BR-29043900 Espirito Santo, Vitoria - Brazil

^[2] Univ Sao Paulo, Sch Phys Educ & Sport, Lab Biochem & Mol Biol Exercise, Av Prof Mello Moraes 65, Cidade Univ, BR-05508900 Sao Paulo, SP - Brazil

• Document type: Review article
• Source: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES; v. 15, n. 4, p. 403-410, 2018.
• Web of Science Citations: 1

Abstract

In the last 10 years the number of studies showing the benefits of resistance training (RT) to the cardiovascular system, have grown. In comparison to aerobic training, RT-induced favorable adaptations to the cardiovascular system have been ignored for many years, thus the mechanisms of the RT-induced cardiovascular adaptations are still uncovered. The lack of animal models with comparable protocols to the RT performed by humans hampers the knowledge. We have used squat-exercise model, which is widely used by many others laboratories. However, to a lesser extent, other models are also employed to investigate the cardiovascular adaptations. In the subsequent sections we will review the information regarding cardiac morphological adaptations, signaling pathway of the cardiac cell, cardiac function and the vascular adaptation induced by RT using this animal model developed by Tamaki et al. in 1992. Furthermore, we also describe cardiovascular findings observed using other animal models of RT. (AU)

• FAPESP's process: 10/09438-0 - THERAPEUTIC USE OF microRNA RESPONSIBLE FOR REGULATING CARDIAC CONTRACTILITY ASSOCIATED WITH EXERCISE TRAINING AEROBIC IN RATS WITH HEART FAILURE
• Grantee: Stéphano Freitas Soares Melo
• Support Opportunities: Scholarships in Brazil - Doctorate