| Full text | |
| Author(s): |
Rueda Furlan, Joao Pedro
[1]
;
Sanchez, Danilo Garcia
[1]
;
Fachin, Ana Lucia
[2]
;
Stehling, Eliana Guedes
[1]
Total Authors: 4
|
| Affiliation: | [1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Ave Cafe S-N, BR-14040903 Ribeirao Preto - Brazil
[2] Univ Ribeirao Preto, Unidade Biotecnol, Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | MICROBIAL DRUG RESISTANCE; v. 24, n. 4, p. 347-352, MAY 2018. |
| Web of Science Citations: | 0 |
| Abstract | |
Burkholderia cepacia complex has emerged as an important opportunistic bacteria group for immunocompromised patients, and it has a high level of intrinsic resistance for different antibiotic classes. Hydrolysis of -lactam antibiotics by -lactamases is the most common resistance mechanism in Gram-negative bacteria, and the presence of such enzymes complicates the selection of appropriate therapy. This study aimed at investigating the antimicrobial resistance profile and the presence of -lactamase encoding genes in B. cepacia complex isolated from Brazilian soils. High-level ceftazidime resistance and several -lactamase encoding genes were found, including the first report of bla(KPC) genes in bacteria isolated from soil. (AU) | |
| FAPESP's process: | 15/18990-2 - Investigation of quinolone resistance mechanisms in environmental bacterial isolates |
| Grantee: | Eliana Guedes Stehling |
| Support Opportunities: | Regular Research Grants |