Discovery of novel anelloviruses in small mammals expands the host range and diversity of the Anelloviridae

Author(s):Show less -

de Souza, William Marciel ^{[1, 2]} ; Fumagalli, Marcilio Jorge ^[1] ; de Araujo, Jansen ^[3] ; Sabino-Santos, Jr., Gilberto ^[1] ; Motta Maia, Felipe Gonsalves ^{[4, 1]} ; Romeiro, Marilia Farignoli ^[1] ; Modha, Sejal ^[2] ; Nardi, Marcello Schiavo ^[5] ; Queiroz, Luzia Helena ^[6] ; Durigon, Edison Luiz ^[3] ; Teixeira Nunes, Marcio Roberto ^{[7, 8]} ; Murcia, Pablo Ramiro ; Moraes Figueiredo, Luiz Tadeu ^[1]

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Virol Res Ctr, Av Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP - Brazil

^[2] Univ Glasgow, Ctr Virus Res, MRC, Glasgow, Lanark - Scotland

^[3] Univ Sao Paulo, Lab Inst Biomed Sci, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil

^[5] Div Tecn Med Vet & Manejo Fauna Silvestre, Sao Paulo, SP - Brazil

^[6] Sao Paulo State Univ, Fac Vet Med, Aracatuba - Brazil

^[7] Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 - USA

^[8] Minist Hlth, Evandro Chagas Inst, Ctr Technol Innovat, Ananindeua, Para - Brazil

• Document type: Journal article
• Source: VIROLOGY; v. 514, p. 9-17, JAN 15 2018.
• Web of Science Citations: 10

Abstract

The Anelloviridae comprises single-stranded DNA viruses currently grouped in sixty-eight species classified in twelve genera. They have been found in many vertebrate hosts including primates. In this study, we describe the application of the high-throughput sequencing to examine the frequency and diversity of anelloviruses in rodents, bats and opossums captured in Sao Paulo State, Brazil. We report a total of twenty-six anelloviruses with sixteen nearly complete genomes and ten partial genomes, which include eleven potential novel species identified in rodents (Cricetidae), bats (Molossidae and Phyllostomidae), and opossums (Didelphidae). We also propose the inclusion of two potential new genera within the Anelloviridae family, provisionally named Omegatorquevirus and Sigmatorquevirus, including six and three novel species of anelloviruses, respectively. In summary, this study expands the diversity and the host range of the known anelloviruses. (AU)

• FAPESP's process: 16/02568-2 - Research on hantavirus and other viruses in wild small mammals and their ectoparasites
• Grantee: Gilberto Sabino dos Santos Junior
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 12/24150-9 - Research of virus in wild rodents, mosquitoes and ticks
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 16/01414-1 - Production of recombinant viral antigenic peptides and development of methods for serological diagnosis of infections by Chikungunya, Mayaro and Zika viruses
• Grantee: Marcilio Jorge Fumagalli
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 14/20851-8 - Study about Alphavirus and Flavivirus infections in samples of blood bank
• Grantee: Marilia Farignoli Romeiro
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 15/05778-5 - Bioinformatics analysis of data of viral metagenomic of animals from Brazil and Antarctica
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• FAPESP's process: 13/14929-1 - Detection of arbovirus and other RNA viruses by real time RT-PCR and study of the viroma
• Grantee: Luiz Tadeu Moraes Figueiredo
• Support Opportunities: Regular Research Grants
• FAPESP's process: 11/06810-9 - Detection and ecology of Hantavirus among wild small mammals and their ectoparasites
• Grantee: Gilberto Sabino dos Santos Junior
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 08/06411-4 - Detection of Hantavirus in rodents and study of dynamics of rodent-reservoir populations in the region of Ribeirão Preto.
• Grantee: Gilberto Sabino dos Santos Junior
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 11/22663-6 - Study of the occurence of arboviroses in wild animals and mosquitoes in Brazilian biomes and agroecosystems
• Grantee: Felipe Gonçalves Motta Maia
• Support Opportunities: Scholarships in Brazil - Doctorate