Solid-phase extractions in flow analysis

Author(s)

Rocha, Fabio R. P. ^[1] ; Batista, Alex D. ^[2] ; Melchert, Wanessa R. ^[3] ; Zagatto, Elias A. G. ^[1]

Affiliation

^[1] Univ Sao Paulo, Ctr Energia Nucl Agr, Ave Centenario 303, BR-13400970 Piracicaba, SP - Brazil

^[2] Univ Fed Uberlandia, Inst Quim, Av Joao Naves de Avila 2121, BR-38408100 Uberlandia, MG - Brazil

^[3] Univ Sao Paulo, Escola Super Agr Luiz de Queiroz, Caixa Postal 9, BR-13418970 Piracicaba, SP - Brazil

• Document type: Journal article
• Source: Anais da Academia Brasileira de Ciências; v. 90, n. 1, 1, p. 803-824, 2018.
• Web of Science Citations: 2

Abstract

Coupling solid-phase extraction (SPE) to flow systems has promoted a synergistic development. Whereas SPE mechanization leads to improved precision and higher sample throughput, as well as diminishes systematic errors and contamination risks, analyte concentration and separation from the sample matrix provides a remarkable impact on detectability and selectivity in flow analysis. Historical aspects, main cornerstones, tips for system design, and recent applications are critically reviewed, in the context of analyte(s) separation/concentration, sample clean-up, and release of sorbed chemical species involving both packed (e.g. mini-columns, cartridges, and disks) or fluidized (e.g. beads and magnetic materials) particles. Novel (bio)sorbents, selective synthetic materials, and stationary phases for low-pressure chromatography are also discussed. Moreover, the feasibility of SPE for sample treatment before chromatographic separation, as well as the exploitation of direct measurements on the solid phase (optosensing) are emphasized. (AU)

• FAPESP's process: 11/23498-9 - Advanced flow systems for technological, agronomical and environmental analysis
• Grantee: Elias Ayres Guidetti Zagatto
• Support Opportunities: Research Projects - Thematic Grants