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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Hydroalcoholic extracts of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves on Streptococcus mutans biofilm and tooth demineralization

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Author(s):
Pires, Juliana Goncalves [1] ; Zabini, Sara Salustiano [1] ; Braga, Aline Silva [1] ; Fabris, Rita de Cassia [1] ; de Andrade, Flaviana Bombarda [2] ; de Oliveira, Rodrigo Cardoso [1] ; Magalhaes, Ana Carolina [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Al Octavio Pinheiro Brisolla 9-75, Bauru, SP - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Operat Dent Endodont & Dent Mat, Al Octavio Pinheiro Brisolla 9-75, Bauru, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: ARCHIVES OF ORAL BIOLOGY; v. 91, p. 17-22, JUL 2018.
Web of Science Citations: 5
Abstract

Objectives: This study evaluated the effect of the hydroalcoholic extracts of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves (alone or combined) on the viability of Streptococcus mutans biofilm and on the prevention of enamel demineralization. Methods: Strain of S. mutans (ATCC 21175) was reactivated in BHI broth. Minimum inhibitory concentration, minimum bactericidal concentration, minimum inhibition biofilm concentration and minimum eradication biofilm concentration were determined in order to choose the concentrations to be tested under biofilm model. S. mutans biofilm (5 x 10(5) CFU/ml) was produced on bovine enamel, using McBain saliva under 0.2% sucrose exposure, for 3 days. The biofilm was daily treated with the extracts for 1 min. The biofilm viability was tested by fluorescence and the enamel demineralization was measured using TMR. Results: Myracrodruon urundeuva All. (Isolated or combined) at the concentrationsc >= 0.625 mg/ml was able to reduce bacteria viability, while Qualea Grandflora Mart. alone had antimicrobial effect at 5 mg/ml only (p < 0.05). On the other hand, none of the extracts were able to reduce enamel demineralization. Conclusions: The hydroalcoholic extracts of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves (isolated or combined) have antimicrobial action; however, they do not prevent enamel caries under S. mutans biofilm model. (AU)

FAPESP's process: 17/00556-0 - Evaluation of the antimicrobial effect of alternative and commercial agents on a microcosm biofilm and on prevention of dental demineralization
Grantee:Ana Carolina Magalhães
Support Opportunities: Regular Research Grants
FAPESP's process: 16/20212-0 - Effect of hydroalcoholic extracts leaves Myracrodruon urundeuva all. and Qualea Grandiflora Mart. on viability of Streptococcus mutans biofilm and prevention of enamel demineralization in vitro
Grantee:Sara Salustiano Zabini
Support Opportunities: Scholarships in Brazil - Scientific Initiation