Immune cell infiltration in Ectomesenchymal chondromyxoid tumor: An immunohistochemical study

Author(s)

Almeida, Luciana Yamamoto ^[1] ; Lopes Dominguete, Matheus Henrique ^[2] ; Dominguete, Paulo Roberto ^[2] ; Ribeiro-Silva, Alfredo ^[1] ; Teixeira, Lucas Ribeiro ^[3] ; Leon, Jorge Esquiche ^[3]

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Med Sch FMRP USP, Dept Pathol & Forens Med, Ribeirao Preto - Brazil

^[2] Univ Vale Rio Verde, Sch Dent, Minas Gerais - Brazil

^[3] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Stomatol Publ Oral Hlth & Forens Dent, Oral Pathol, Ribeirao Preto - Brazil

• Document type: Letter
• Source: Oral Oncology; v. 81, p. 112-115, JUN 2018.
• Web of Science Citations: 2

Abstract

Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign neoplasm, often affecting the anterior dorsum of the tongue. To date, approximately 74 cases of lingual ECT have been published. This report describes, for the first time, the morphological and immunohistochemical features of a unique ECT case, which revealed diffuse infiltration by immune cells with a dendritic-like appearance inside the tumor proliferation. The significance of these findings and discussion about the tumor cell-immune cell interactions are presented. (AU)

• FAPESP's process: 16/11419-0 - Clinicopathological correlation of the degree of differentiation, tetraspanin expression, viral agents and cell proliferation in a large sample of squamous cell carcinoma of the head and neck region.
• Grantee: Jorge Esquiche León
• Support Opportunities: Regular Research Grants
• FAPESP's process: 11/52090-8 - Comparative immunohistochemical analysis of dendritic cells, cytotoxic lymphocytes, and indolamine 2,3-dioxigenase expression in potentially malignant disorders and squamous cells carcinoma of the oral cavity and lower lip
• Grantee: Jorge Esquiche León
• Support Opportunities: Regular Research Grants