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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Polygonal Model: A Simple Representation of Biomolecules as a Tool for Teaching Metabolism

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Author(s):
Sampaio Bonafe, Carlos Francisco [1] ; Conceicao Bispo, Jose Ailton [2] ; de Jesus, Marcelo Bispo [1]
Total Authors: 3
Affiliation:
[1] Univ Campinas UNICAMP, Inst Biol, Dept Biochem & Tissue Biol, BR-13083970 Campinas, SP - Brazil
[2] Univ Feira Santana UEFS, Fac Food Engn, Dept Technol, CP 252-294, BR-44036900 Feira De Santana, BA - Brazil
Total Affiliations: 2
Document type: Journal article
Source: BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION; v. 46, n. 1, p. 66-75, JAN-FEB 2018.
Web of Science Citations: 0
Abstract

Metabolism involves numerous reactions and organic compounds that the student must master to understand adequately the processes involved. Part of biochemical learning should include some knowledge of the structure of biomolecules, although the acquisition of such knowledge can be time-consuming and may require significant effort from the student. In this report, we describe the ``polygonal model{''} as a new means of graphically representing biomolecules. This model is based on the use of geometric figures such as open triangles, squares, and circles to represent hydroxyl, carbonyl, and carboxyl groups, respectively. The usefulness of the polygonal model was assessed by undergraduate students in a classroom activity that consisted of ``transforming{''} molecules from Fischer models to polygonal models and vice and versa. The survey was applied to 135 undergraduate Biology and Nursing students. Students found the model easy to use and we noted that it allowed identification of students' misconceptions in basic concepts of organic chemistry, such as in stereochemistry and organic groups that could then be corrected. The students considered the polygonal model easier and faster for representing molecules than Fischer representations, without loss of information. These findings indicate that the polygonal model can facilitate the teaching of metabolism when the structures of biomolecules are discussed. Overall, the polygonal model promoted contact with chemical structures, e.g. through drawing activities, and encouraged student-student dialog, thereby facilitating biochemical learning. (C) 2017 by The International Union of Biochemistry and Molecular Biology. (AU)

FAPESP's process: 14/03002-7 - Internalization and intracellular trafficking of nanoparticles: biological activity and nanotoxicological profile
Grantee:Marcelo Bispo de Jesus
Support Opportunities: Research Grants - Young Investigators Grants