Effect of different concentrations and application times of proanthocyanidin gels on dentin erosion

Author(s)

Boteon, Ana Paula ^[1] ; Prakki, Anuradha ^[2] ; Rabelo Buzalaf, Marilia Afonso ^[3] ; Rios, Daniela ^[4] ; Honorio, Heitor Marques ^[4]

Affiliation

^[1] Univ Sao Paulo, Bauru Sch Dent, Dept Restorat Dent Endodont & Dent Mat, Sao Paulo - Brazil

^[2] Univ Toronto, Fac Dent, Dept Clin Sci Restorat, Toronto, ON - Canada

^[3] Univ Sao Paulo, Bauru Sch Dent, Dept Biol Sci, Sao Paulo - Brazil

^[4] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, Sao Paulo - Brazil

• Document type: Journal article
• Source: AMERICAN JOURNAL OF DENTISTRY; v. 30, n. 2, p. 96-100, APR 2017.
• Web of Science Citations: 2

Abstract

Purpose: To analyze the effect of different concentrations and application times of proanthocyanidin gels on dentin before an erosive challenge in order to evaluate if there is a dose-response or application time-response relationship in the use of these gels for erosion prevention. Methods: 80 bovine root dentin blocks were randomly and equally divided into 10 groups and treated according to the two factors under study (purified grape seed proanthocyanidin gel concentration and time of application): 0.05P1: 0.05% proanthocyanidin gel during 1 minute; 0.05P5: 0.05% proanthocyanidin gel during 5 minutes; 1P1: 1% proanthocyanidin gel during 1 minute; 1P5: 1% proanthocyanidin gel during 5 minutes; 5P1: 5% proanthocyanidin gel during 1 minute; 5P5: 5% proanthocyanidin gel during 5 minutes; 10P1: 10% proanthocyanidin gel during 1 minute; 10P5: 10% proanthocyanidin gel during 5 minutes; Control 1: placebo gel during 1 minute; and Control 5: placebo gel during 5 minutes. The gels were applied over dentin blocks once before the first erosive challenge. After that, the blocks were subjected to three erosive cycles per day, during 5 days. Profilometry was used to quantify the dentin loss (mu m). Data were analyzed by two-way ANOVA and Fisher's test (P< 0.05). Results: Statistical analysis showed that there was no significant difference between the application times. The different concentrations of proanthocianidin gels presented similar results (P> 0.05). All tested gels resulted in significantly less wear when compared to the placebo gel. (AU)

• FAPESP's process: 14/26754-4 - Inhibitory effect of organic matrix degradation and wear of Cranberry and proanthocyanidin gels on dentin submitted to dental erosion
• Grantee: Heitor Marques Honório
• Support Opportunities: Regular Research Grants