Biomimetic Mineralizing Agents Recover the Micro Tensile Bond Strength of Demineralized Dentin

Author(s)

Barbosa-Martins, Luiz Filipe ^[1] ; de Sousa, Jossaria Pereira ^[1] ; Alves, Livia Araujo ^[2] ; Davies, Robert Philip Wynn ^[3] ; Puppin-Rontanti, Regina Maria ^{[1, 4]}

Affiliation

^[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Pediat Dent, BR-13414903 Piracicaba - Brazil

^[2] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Oral Diag, BR-13414903 Piracicaba - Brazil

^[3] Univ Leeds, Sch Dent, Fac Med & Hlth, Div Oral Biol, Leeds LS9 7TF, W Yorkshire - England

^[4] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Restorat Dent, BR-13414903 Piracicaba - Brazil

• Document type: Journal article
• Source: MATERIALS; v. 11, n. 9 SEP 2018.
• Web of Science Citations: 2

Abstract

Biomimetic remineralization is an approach that mimics natural biomineralization, and improves adhesive procedures. The aim of this paper was to investigate the influence of Dentin Caries-like Lesions (DCLL)-Producing Model on microtensile bond strength (mu TBS) of etch and rinse adhesive systems and investigate the effect of remineralizing agents such as Sodium Fluoride (NaF), MI Paste (TM) (MP) and Curodont (TM) Repair (CR) on caries-affected dentin (n = 6). Nine groups were established: (1) Sound dentin; (2) Demineralized dentin/Chemical DCLL: (3) Demineralized dentin/Biological DCLL; (4) Chemical/DCLL + NaF; (5) Chemical/DCLL + MP; (6) Chemical/DCLL + CR; (7) Biological/DCLL + NaF; (8) Biological/DCLL + MP; (9) Biological/DCLL + CR. Then all dentin blocks were subjected to a bonding procedure with Adper (TM) Single Bond 2 adhesive system/Filtek Z350XT 4 mm high block, following this they were immersed in deionized water/24 h and then sectioned with congruent to 1 mm(2) beams. The mu TBS test was conducted at 1 mm/min/500 N loading. Failure sites were evaluated by SEM (scanning electron microscopy (150x). mu TBS data were submitted to factorial ANOVA and Tukey's test (p < 0.05). The highest values were found when demineralized dentin was treated with MP and CR, regardless caries lesion depth (p < 0.05). There was a predominance of adhesive/mixed in the present study. It was concluded that the use of the artificial dentin caries production models produces differences in the mu TBS. Additionally MP and CR remineralizing agents could enhance adhesive procedures even at different models of caries lesion. (AU)

• FAPESP's process: 11/16634-3 - Evalution of resistance of union the affected dentin caries for post treatment by diferente substances capacity remineralizing
• Grantee: Luiz Filipe Barbosa Martins
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 15/12660-0 - Effect of remineralizing agents on proteolytic activity and resin/caries-affected dentin bond longevity
• Grantee: Regina Maria Puppin Rontani
• Support Opportunities: Regular Research Grants