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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Towards the production of natural rubber-calcium phosphate hybrid for applications as bioactive coatings

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Author(s):
do Nascimento, Rodney Marcelo [1] ; de Paula, Amauri Jardim [2] ; Oliveira, Naiara Cipriano [2] ; Alves, Ana Cecilia [2] ; Lima de Oliveira Aquino, Yasmine Maria [2] ; Souza Filho, Antonio Gomes [2] ; Figueiredo Soares Rodrigues, Joao Elias [1] ; Hernandes, Antonio Carlos [1]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Sao Carlos Inst Phys, POB 369, BR-13566590 Sao Carlos, SP - Brazil
[2] Univ Fed Ceara, Dept Fis, POB 6030, BR-60455900 Fortaleza, CE - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Materials Science & Engineering C-Materials for Biological Applications; v. 94, p. 417-425, JAN 1 2019.
Web of Science Citations: 0
Abstract

This paper assesses the morphological, structural and bio-physicochemical stability of natural rubber (NR) Hevea brasiliensis coatings incorporated with microparticles of calcium phosphate-based (CaP) bioactive ceramics. Optical and electronic spectroscopic imaging techniques were employed to successfully evaluate the NR encapsulation capability and the stability of the coating in a biologically relevant media for bio-related application, i.e., simulated body fluid (SBF). The chemical structure of the natural polymer, the microchemical environment at the NR-CaP interface and the morphology of the CaP clusters were fully characterized. Further, the response of the hybrid coating to SBF was evaluated by incubating the samples for 30 days. The hybrid coating formed on Si surface (inert substrate) exhibited both stability and biodegradability in different levels (time dependence), thus opening horizons for applications as coatings for both biomaterials and drug delivery systems. (AU)

FAPESP's process: 13/21970-8 - Development of biomaterial from the incorporation of calcium phosphates in latex structures to order application as controlled release device
Grantee:Rodney Marcelo do Nascimento
Support Opportunities: Scholarships in Brazil - Post-Doctoral