Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A Metabolomic Overview of Follicular Fluid in Cows

Full text
Author(s):
Guerreiro, Tatiane Melina [1] ; Goncalves, Roseli Fernandes [2] ; Rodrigues Melo, Carlos Fernando O. [1] ; de Oliveira, Diogo Noin [1] ; Lima, Estela de Oliveira [1] ; Visintin, Jose Antonio [2] ; de Achilles, Marcos Antonio [3] ; Catharino, Rodrigo Ramos [1]
Total Authors: 8
Affiliation:
[1] Univ Estadual Campinas, UNICAMP, Sch Pharmaceut Sci, Innovare Biomarkers Lab, Campinas, SP - Brazil
[2] Sao Paulo Univ USP, Coll Vet Med & Anim Sci, Dept Anim Reprod, Sao Paulo - Brazil
[3] Achilles Genet, Garca - Brazil
Total Affiliations: 3
Document type: Journal article
Source: FRONTIERS IN VETERINARY SCIENCE; v. 5, FEB 8 2018.
Web of Science Citations: 5
Abstract

Follicular fluid (FF) protects the oocyte against proteolysis and extrusion during ovulation, providing an appropriate microenvironment that favors proper embryonic development; thereby, FF plays a key role in embryo quality. Being directly related to cattle breeding, studying FF is extremely important in livestock science to measure cattle fertility. This may eventually help to assess the quality of both meat and milk, products widely consumed worldwide. There is an important commercial interest in the evaluation and characterization of compounds present in the FF of livestock that present greater likelihood of pregnancy. Mass spectrometry is a great ally for this type of analysis and can provide quick and efficient screening for molecular markers in biological samples. The present study demonstrated the potential of high-resolution mass spectrometry in analyzing FF samples from two distinct groups of Nellore cows (Bos indicus): high and low fertility, as determined by the number of oocytes produced. We were able to delineate markers of interest for each group, which may ultimately be related to biochemical pathways that lead to higher or lower reproductive performance. (AU)

FAPESP's process: 10/01077-9 - Identifying biomarkers for embryo biotechnologies through proteomics and lipid fingerprinting of bovine embryos
Grantee:Roseli Fernandes Gonçalves
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 15/06809-1 - Determination of chemical markers in various bovine products using mass spectrometry
Grantee:Rodrigo Ramos Catharino
Support type: Regular Research Grants
FAPESP's process: 11/18085-7 - Identifying biomarkers for embryo biotechnologies through proteomics and lipid fingerprinting of bovine embryos
Grantee:Roseli Fernandes Gonçalves
Support type: Scholarships in Brazil - Young Researchers
FAPESP's process: 11/50400-0 - Mitochondrial energy metabolism, redox state and functionality in cell death and cardiometabolic and neurodegenerative disorders
Grantee:Aníbal Eugênio Vercesi
Support type: Research Projects - Thematic Grants
FAPESP's process: 16/17066-2 - Metabolomics and lipidomics the Zika virus, from mosquitoes to the patient
Grantee:Carlos Fernando Odir Rodrigues Melo
Support type: Scholarships in Brazil - Doctorate