Studies Toward the Synthesis of Caramboxin Analogues

Oliveira Filho, Ronaldo E.; Higa, Vanessa M.; Omori, Alvaro T.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Studies Toward the Synthesis of Caramboxin Analogues

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Author(s):	Oliveira Filho, Ronaldo E. ^[1] ; Higa, Vanessa M. ^[1] ; Omori, Alvaro T. ^[1] Total Authors: 3
Affiliation:	^[1] Univ Fed ABC, Ctr Ciencias Nat & Humans, BR-09210580 Santo Andre, SP - Brazil Total Affiliations: 1
Document type:	Journal article
Source:	Journal of the Brazilian Chemical Society; v. 30, n. 3, SI, p. 528-540, MAR 2019.
Web of Science Citations:	0
Abstract
Intrigued by the recent discovery of caramboxin by Brazilian researchers, we present the results from our studies toward the racemic synthesis of caramboxin analogs through the ortho-carboxylation of 3,5-dimethoxy benzyl derivatives. Three different approaches were tested, and the route involving a Vilsmeier-Haack formylation followed by a Lindgren oxidation provide a potential intermediate for the synthesis of several caramboxin analogs. (AU)

FAPESP's process:	14/25659-8 - Studies aiming the asymmetric total synthesis of caramboxin
Grantee:	Alvaro Takeo Omori
Support Opportunities:	Regular Research Grants

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