CaP Coating and Low-Level Laser Therapy to Stimulate Early Bone Formation and Improve Fixation of Rough Threaded Implants

Author(s)

do Prado, Renata Falchete ^[1] ; El Abras Ankha, Milagros del Valle ^[2] ; Griti Bueno, Daiane Acacia ^[1] ; de Souza Santos, Evelyn Luzia ; Pereira Tini, Italo Rigotti ^[2] ; Ramos, Carolina Judica ^{[3, 4]} ; Spalding, Marianne ^[1] ; Oliveira de Vasconcellos, Luis Gustavo ^[5] ; Reis de Vasconcellos, Luana Marotta ^[1]

Affiliation

^[1] Univ Estadual Paulista, UNESP, Inst Ciencia & Tecnol, Dept Biosci & Oral Diag, Sao Jose Dos Campos - Brazil

^[2] Univ Estadual Paulista, UNESP, Inst Ciencia & Tecnol, Oral Biopathol, Dept Biosci & Oral Diag, Sao Jose Dos Campos - Brazil

^[3] Univ Estadual Paulista, UNESP, Inst Ciencia & Tecnol, Dept Social Dent, Sao Jose Dos Campos - Brazil

^[4] Univ Estadual Paulista, UNESP, Inst Ciencia & Tecnol, Childrens Clin, Sao Jose Dos Campos - Brazil

^[5] Univ Estadual Paulista, UNESP, Inst Ciencia & Tecnol, Dept Prosthodont & Dent Mat, Sao Jose Dos Campos - Brazil

• Document type: Journal article
• Source: IMPLANT DENTISTRY; v. 27, n. 6, p. 660-666, DEC 2018.
• Web of Science Citations: 1

Abstract

Purpose: This study aimed to compare in vivo osteogenesis on rough threaded dental implants with and without calcium phosphate (CaP) coating deposition, alone or in association with low-level laser therapy (LLLT) by gallium aluminum arsenide. Material and Methods: Four groups were studied: G1: implant; G2: implant + CaP coating; G3: implant + LLLT; and G4: implant + CaP coating + LLLT. LLLT was applied for 7 days at the surgical site before and after placing the implant. Topographic characterization was performed before surgery using scanning electron microscopy and energy dispersion spectrophotometry. Bone-implant contact (BIC) was measured after 1, 2, and 6 weeks and reverse torque after 6 weeks. In short periods, G2, G3, and G4 showed significantly greater BIC than G1 (P < 0.05), but no difference in BIC was observed at 6 weeks. However, the values for the removal torque test at 6 weeks were higher in G2 and G4 (P < 0.05). Conclusion: Both CaP coating alone and using LLLT induce cellular stimulation and improve BIC in short-term healing, resulting in higher implant fixation, and should be considered in clinical practice due to their low cost and high effectiveness. (AU)

• FAPESP's process: 12/22158-2 - Comparative in vivo study of bone ingrowth in porous titanium alloys samples processed via powder metallurgy
• Grantee: Daiane Acacia Griti Bueno
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 11/17392-3 - Influence of low intensity laser and biomimetic treatment on osseointegration: histological and biomechanical analyses in rabbits
• Grantee: Luana Marotta Reis de Vasconcellos
• Support Opportunities: Regular Research Grants