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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Nanomaterials in the Environment: Perspectives on in Vivo Terrestrial Toxicity Testing

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Author(s):
Mendonca, Monique C. P. [1] ; Rizoli, Cintia [1] ; Avila, Daiana S. [2] ; Amorim, Monica J. B. [3] ; de Jesus, Marcelo B. [1]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Inst Biol, Dept Biochem & Tissue Biol, Campinas, SP - Brazil
[2] Fed Univ Pampa, Uruguaiana - Brazil
[3] Univ Aveiro, Dept Biol & CESAM, Aveiro - Portugal
Total Affiliations: 3
Document type: Review article
Source: FRONTIERS IN ENVIRONMENTAL SCIENCE; v. 5, 2017.
Web of Science Citations: 1
Abstract

Over the last decade, engineered nanomaterials (NMs) brought a revolutionary development in many sectors of human life including electronics, paints, textiles, food, agriculture, and health care. However, the exponential growth in the number of NMs applications resulted in uncertainties regarding their environmental impacts. Currently, the common approach for assessing the toxicity of NMs such as, carbon-(fullerenes, single-and multi-walled carbon nanotubes), mineral-(gold and silver nanoparticles, ceriumand zinc oxide, silicon and titaniumdioxide), and organic-based NMs (dendrimers) includes standard guidelines applied to all chemical compounds. Nevertheless, NMs differ from traditional materials as their physicochemical and surface properties influence the toxic rather than their composition alone. Considering such NMs specificities, adaptations in some methods are necessary to ensure that environmental and human health risks are accurately investigated. In this context, the focus of this mini-review is to summarize the current knowledge in nanotoxicology regarding relevant organisms and experimental assays for assessing the terrestrial toxicity of NMs. (AU)

FAPESP's process: 14/03002-7 - Internalization and intracellular trafficking of nanoparticles: biological activity and nanotoxicological profile
Grantee:Marcelo Bispo de Jesus
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 16/03765-6 - In vitro and in vivo determination of toxicological profile of nanoformulations
Grantee:Monique Culturato Padilha Mendonça
Support Opportunities: Scholarships in Brazil - Post-Doctoral