Effect of synthetic colloidal nanoparticles in acrylic resin of dental use

Author(s)

de Souza Neto, Francisco Nunes ^[1] ; Sala, Renata Lang ^[1] ; Fernandes, Renan Aparecido ^[2] ; Oliveira Xavier, Tatielih Pardim ^[3] ; Cruz, Sandra Andrea ^[1] ; Paranhos, Caio Marcio ^[1] ; Monteiro, Douglas Roberto ^{[2, 4]} ; Barbosa, Debora Barros ^[2] ; Botazzo Delbem, Alberto Carlos ^[2] ; de Camargo, Emerson Rodrigues ^[1]

Affiliation

^[1] Fed Univ Sao Carlos UFSCar, Dept Chem, Interdisciplinary Lab Electrochem & Ceram LIEC, Rod Washington Luis, Km 235, BR-13565905 Sao Carlos, SP - Brazil

^[2] State Univ Sao Paulo UNESP, Aracatuba Dent Sch, Dept Pediat Dent & Publ Hlth, Rua Jose Bonifacio 1193, BR-16015050 Aracatuba, SP - Brazil

^[3] Fed Inst Educ Sci & Technol Goias, Campus Uruacu IFG, Rua Formosa, Qd 28 & 29, BR-76400000 Uruacu, Go - Brazil

^[4] Univ Western Sao Paulo UNOESTE, GPD, Rua Jose Bongiovani 700, BR-19050920 Presidente Prudente, SP - Brazil

• Document type: Journal article
• Source: EUROPEAN POLYMER JOURNAL; v. 112, p. 531-538, MAR 2019.
• Web of Science Citations: 0

Abstract

Acrylic resin employed in dental materials can act as substrate for microorganisms' adhesion and biofilm formation. To overcome this, silver nanoparticles (AgNPs) were combined with poly(methyl methacrylate) (PMMA) to reduce denture stomatitis caused by Candida glabrata. Although AgNPs antimicrobial activity is already known, the physicochemical properties of its nanocomposites, which dictate the performance of these commercial targets remain little explored. We evaluated the effect of different amount of AgNPs in PMMA obtained by the thermal polymerization. Among the mechanical tests employed, PMMA flexural strength decreased with higher AgNPs concentration. The microbiological adhesion test against Candida glabrata revealed the nano composite with 0.05% of AgNPs has greater capacity to inhibit the biofilm formed on its surface. Although we observed distinct thermo-mechanical behavior in the presence of AgNPs, antimicrobial property was not linearly dependent of nanoparticles concentration and was influenced by nanoparticles dispersion and distribution in the polymer matrix. (AU)

• FAPESP's process: 15/13958-3 - Nanocomposite biomaterials based on thermoresponsive HIDROGELS
• Grantee: Emerson Rodrigues de Camargo
• Support type: Regular Research Grants
• FAPESP's process: 12/07067-0 - Photocatalyst based in bismuth titanate synthesized by the oxidant peroxo method (OPM)
• Grantee: Emerson Rodrigues de Camargo
• Support type: Regular Research Grants
• FAPESP's process: 12/17880-0 - Effect of the insertion of synthetic nanoparticles prepared by colloidal route in a commercial acrylic matrix of dental use.
• Grantee: Francisco Nunes de Souza Neto
• Support type: Scholarships in Brazil - Doctorate