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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of symmetrical biaryl compounds by homocoupling reaction

Full text
Author(s):
Vasconcelos, Stanley N. S. [1] ; Reis, Joel S. [1] ; de Oliveira, Isadora M. [2] ; Balfour, Michael N. [1] ; Stefani, Helio A. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Inst Quim, Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Tetrahedron; v. 75, n. 13, p. 1865-1959, MAR 29 2019.
Web of Science Citations: 5
Abstract

Since the development of the Ullmann coupling in the early 20th Century, there has been intense and continuous research on the syntheses of biaryl compounds, which appears as an interesting branch of organic chemistry. A myriad of methodologies for the synthesis of biaryl compounds have been studied and well established, including homocoupling methodologies, which in general are robust as well as consolidated strategies. Biaryl systems are quite relevant building blocks for the synthesis of more complex chemical structures. Besides the diversity of functional groups that can be used to promote a new aryl-aryl bond, there is a wide variety of transition metals that can act as catalyst in these processes. In this review, we summarized numerous methodologies of homocoupling reactions for the synthesis of symmetrical biaryl compounds. (C) 2019 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 13/17960-7 - Functionalization of 3-iodo-(L)-Tyrosine via Suzuki-Miyaura Reaction Using Potassium Organotrifluoroborate salts
Grantee:Stanley Nunes Siqueira Vasconcelos
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 16/04289-3 - Synthesis of calcogeno amino acids derivatives and 4-calcogeno quinolines via multicomponent reactions
Grantee:Isadora Maria de Oliveira
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 17/24821-4 - Carbonylative Coupling and Intramolecular Cycloaddition [2 + 2] Reactions Employing D-Glucal
Grantee:Helio Alexandre Stefani
Support Opportunities: Regular Research Grants
FAPESP's process: 14/19221-0 - Synthesis of libraries for use in biological testing of Chagas Disease
Grantee:Michael Nils Balfour
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 16/02392-1 - 2-Aryloxazolines: Synthesis, Biological Activity and Fluorescence
Grantee:Joel Savi dos Reis
Support Opportunities: Scholarships in Brazil - Post-Doctoral