| Full text | |
| Author(s): |
José Roberto CORTELLI
[1]
;
Regina Márcia Serpa PINHEIRO
[2]
;
Fernando de Oliveira COSTA
[3]
;
Davi Romeiro AQUINO
[4]
;
Suzane A RASLAN
[5]
;
Sheila Cavalca CORTELLI
[6]
Total Authors: 6
|
| Affiliation: | [1] Universidade de Taubaté. Faculdade de Odontologia - Brasil
[2] Faculdade de Odontologia. Centro de Ensino São Lucas - Brasil
[3] Universidade Federal de Minas Gerais. Faculdade de Odontologia - Brasil
[4] Universidade de Taubaté. Faculdade de Odontologia - Brasil
[5] Universidade de Taubaté. Faculdade de Odontologia - Brasil
[6] Universidade de Taubaté. Faculdade de Odontologia - Brasil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Rev. odontol. UNESP; v. 43, n. 3, p. 196-202, 2014-06-00. |
| Abstract | |
Background: Several studies have investigated the differences in salivary parameters and microbial composition between diabetic and non-diabetic patients, however, specific differences are still not clear mainly due to the effects of confounder.Aim: The aim of this case-control study was to evaluate the salivary and microbial parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus.Material and method: This case-control study included 60 chronic periodontitis subjects, 30 diabetics (case group) and 30 non-diabetics (control group), paired according to periodontitis severity, gender and age. Stimulated whole saliva was collected from all volunteers to measure the salivary pH and the salivary flow rate. Bacterial samples were collected with paper points from periodontal sites showing the deepest periodontal pocket depth associated with the highest clinical attachment loss. The frequency of A. actinomycetemcomitans, P. intermedia, P. gingivalis, T. forsythiaand C. rectuswas evaluated by PCR. Data was statistically analyzed by Student's t, Mann-Whitney and Chi-square (p<0.05).Result: Diabetic subjects showed higher salivary glucose levels and lower stimulated flow rates in comparison to non-diabetic controls. P. gingivalisand T. forsythia were the most frequent pathogens (p<0.05). Bacterial frequency did not differ between case and control groups.Conclusion: Diabetes status influenced salivary glucose levels and flow rate. Within the same severity of chronic periodontitis, diabetic subjects did not show higher frequency of periodontal pathogens in comparison to their paired controls. (AU) | |
| FAPESP's process: | 11/02371-0 - Evaluation of gingival therapy in diabetic, obese or diabetic/obese subjects |
| Grantee: | Suzane A Raslan |
| Support Opportunities: | Scholarships in Brazil - Doctorate |