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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Endodontic Sealers Modified with Silver Vanadate: Antibacterial, Compositional, and Setting Time Evaluation

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Vilela Teixeira, Ana Beatriz [1] ; Honorato Silva, Caroline de Carvalho [1] ; Alves, Oswaldo Luiz [2] ; dos Reis, Andrea Candido [1]
Total Authors: 4
[1] Univ Sao Paulo, Ribeirao Preto Sch Dent, Dent Mat & Prosthesis Dept, BR-14040904 Ribeirao Preto, SP - Brazil
[2] Univ Campinas Unicamp, Inst Chem, Lab Solid State Chem, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Web of Science Citations: 0

The incorporation of nanoparticles into endodontic sealers aims at increasing antimicrobial activity of the original material. Aim. The aim of this study is to incorporate the nanostructured silver vanadate decorated with silver nanoparticles (AgVO3, at 2.5%, 5%, and 10%) into three endodontic sealers and evaluate the antibacterial activity of freshly sealers, surface topography and chemical composition, and setting time. Material and Methods. The AgVO3 was incorporated into AH Plus, Sealer 26, and Endomethasone N at concentrations 0%, 2.5%, 5%, and 10% (in mass). The antibacterial activity of freshly sealers was assessed by direct contact with Enterococcus faecalis and CFU/mL count (n=10), surface topography, and chemical composition were measured by SEM/EDS, and the setting time was measured by Gillmore needle (n=10). The Kruskal-Wallis and Dunn statistical tests were applied (=0.05). Results. All groups of sealers evaluated inhibited E. faecalis (p>0.05). The incorporation of AgVO3 altered the atomic proportions between components of the endodontic sealers, and the percentage of silver (Ag) and vanadium (V) increased proportionally to the concentrations of AgVO3. Topography analysis showed differences in components distribution on the surface of the specimens. The sealers incorporated with AgVO3 of AH Plus presented a lower setting time than the control group (p<0.05). For Sealer 26 and Endomethasone N, the incorporation of AgVO3 increased the setting time in relation to control group (p<0.05). Conclusions. The modification of endodontic sealers by AgVO3 increased the atomic percentage of Ag and V proportionally to the concentration of the nanomaterial and changed the atomic percentage of the sealer components and setting times. It cannot be affirmed that the AgVO3 promote differences in the antimicrobial activity of freshly sealers, and further investigations of the antimicrobial activity of the set sealers should be carried out. (AU)

FAPESP's process: 17/04667-0 - Evaluation of endodontic sealers incorporated with silver vanadate nanostructured decorated with silver nanoparticles for toxicity, antimicrobial and physicochemical properties
Grantee:Ana Beatriz Vilela Teixeira
Support type: Scholarships in Brazil - Doctorate