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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Production and characterization of solid lipid microparticles loaded with guarana (Paullinia cupana) seed extract

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Silva, Marluci P. [1] ; Thomazini, Marcelo [1] ; Holkem, Augusto T. [1] ; Pinho, Lorena S. [1] ; Genovese, Maria I. [2] ; Favaro-Trindade, Carmen S. [1]
Total Authors: 6
[1] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos, Dept Engn Alimentos, Pirassununga, SP - Brazil
[2] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Alimentos & Nutr Expt, Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Food Research International; v. 123, p. 144-152, SEP 2019.
Web of Science Citations: 2

Guarana is a native fruit of the Amazon rainforest, which presents high levels of phenolic compounds. However, these bioactive compounds may be unstable in food processing and gastrointestinal conditions. Thus, this work aimed to characterize guarana seed extract (GSE) followed by microencapsulation using a spray-chilling method and with vegetable fat as carrier, as well as to evaluate the particles. Phenolic-rich GSE was produced using 50% (w/w) hydroalcoholic solution and dehydrated by spray drying and lyophilization. Powdered GSE was characterized in relation to its inhibitory activity on digestive enzymes. Solid lipid microparticles (SLM) were evaluated for the retention of bioactive compounds and the release profile of phenolic compounds in simulated gastrointestinal conditions. Powdered GSE showed anti-obesity potential due to the high inhibitory activity of lipase. Regarding the retention of phenolic compounds, at least 75% were detected after 90 days at 25 degrees C in SLM. Moreover, SLM loaded with 7.5% GSE released approximately 99% of phenolic compounds in simulated gastrointestinal conditions. These results show the efficiency of spray chilling for protection and release of phenolic compounds from GSE, allowing future application in food. (AU)

FAPESP's process: 16/24895-5 - Coencapsulation of guarana extracts (Paullinia cupana) and probiotics
Grantee:Marluci Palazzolli da Silva
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 16/24916-2 - Preparation, encapsulation and application of extract of carotenoids obtained from the bark of guarana (Paullinia cupana)
Grantee:Lorena Silva Pinho
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 18/05315-3 - Chemo-preventive properties of extracts from blueberries, jabuticabas and cinnamon isolated or combined with probiotics
Grantee:Augusto Tasch Holkem
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/19375-0 - Coencapsulation of probiotics and proanthocyanidin-rich extract obtained from cinnamon (Cinnamomum zeylanicum Blume)
Grantee:Augusto Tasch Holkem
Support type: Scholarships in Brazil - Doctorate