Development of an Impression Material with Antimicrobial Properties for Dental Application

Author(s)

de Castro, Denise T. ^{[1, 2]} ; Kreve, Simone ^[1] ; Oliveira, Viviane C. ^[1] ; Alves, Oswaldo L. ^[3] ; dos Reis, Andrea C. ^[1]

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Dent Sch, Dept Dent Mat & Prosthodont, Ribeirao Preto, SP - Brazil

^[2] Sch Dent Uberaba, Dept Biomat, Uberaba, MG - Brazil

^[3] State Univ Campinas UNICAMP, Dept Inorgan Chem, Campinas, SP - Brazil

• Document type: Journal article
• Source: JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY; v. 28, n. 8 AUG 2019.
• Web of Science Citations: 0

Abstract

Purpose To evaluate the antimicrobial activity and physico-mechanical properties of an irreversible hydrocolloid in which nanostructured silver vanadate decorated with silver nanoparticles (AgVO3) was added at various concentrations (0% - control, 2.5%, 5%, and 10% by weight). Materials and Methods The agar diffusion method (n = 10) was used to evaluate the inhibitory effect on the following species: Streptococcus mutans, Staphyloccocus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. The gelation time, flow capacity and plastic deformation were verified (n = 10). The data were analyzed using the Kruskal-Wallis test followed by the Dunn post-test, or via one-way ANOVA with multiple comparisons with a Bonferroni adjustment depending on the distribution (alpha = 0.05). Results All percentages of the nanomaterial were able to promote the antimicrobial activity of a hydrocolloid, with the formation of an inhibition zone (p < 0.05). In general, there was a dose-dependent effect on antimicrobial activity: higher concentrations of the nanomaterial promoted greater action except in the cases of P. aeruginosa (p < 0.001; F = 51.74) and S. aureus (p < 0.001), where the highest inhibition was for the 2.5% group. No difference was found in the gelation time when the control was compared with the groups with AgVO3 (p > 0.05). The difference was between the 5% and 10% groups (p = 0.007), and the latter promoted an increase in time. The flow capacity of the hydrocolloid with 5% of AgVO3 was significantly lower when compared with the control (p = 0.034). The AgVO3 influenced the plastic deformation (p < 0.001) in such a way that concentrations of 5% (p = 0.010) and 10% (p < 0.001) promoted an increase in this property when compared with the control. Conclusions AgVO3 can be incorporated into an irreversible hydrocolloid as an antimicrobial agent without promoting adverse effects on physical-mechanical properties when used in concentrations of 2.5%. (AU)

• FAPESP's process: 14/25793-6 - Analysis of physico-chemical, mechanical and biological properties of dental acrylic resin synthesized by different methods.
• Grantee: Denise Tornavoi de Castro
• Support Opportunities: Scholarships in Brazil - Doctorate